Difference between revisions of "YGL071W"
SGDwikiBot (talk | contribs) (Automated import of articles) |
SGDwikiBot (talk | contribs) (Automated import of articles) |
||
| Line 18: | Line 18: | ||
|} | |} | ||
<br> | <br> | ||
| − | '''Description of YGL071W:''' Transcription factor involved in iron utilization and homeostasis; binds the consensus site PyPuCACCCPu and activates the expression of target genes in response to changes in iron availability<ref name='S000075799'>Shakoury-Elizeh M, et al. (2004) Transcriptional remodeling in response to iron deprivation in Saccharomyces cerevisiae. Mol Biol Cell 15(3):1233-43 {{SGDpaper|S000075799}} PMID 14668481</ref><ref name='S000053105'>Yamaguchi-Iwai Y, et al. (1996) Iron-regulated DNA binding by the AFT1 protein controls the iron regulon in yeast. EMBO J 15(13):3377-84 | + | '''Description of YGL071W:''' Transcription factor involved in iron utilization and homeostasis; binds the consensus site PyPuCACCCPu and activates the expression of target genes in response to changes in iron availability; in iron-replete conditions activity is negatively regulated by Grx3p, Grx4p, and Fra2p, which regulate Aft1p translocation from the nucleus to the cytoplasm<ref name='S000139086'>Li H, et al. (2011) Histidine 103 in Fra2 Is an Iron-Sulfur Cluster Ligand in the [2Fe-2S] Fra2-Grx3 Complex and Is Required for in Vivo Iron Signaling in Yeast. J Biol Chem 286(1):867-76 {{SGDpaper|S000139086}} PMID 20978135</ref><ref name='S000119477'>Pujol-Carrion N, et al. (2006) Glutaredoxins Grx3 and Grx4 regulate nuclear localisation of Aft1 and the oxidative stress response in Saccharomyces cerevisiae. J Cell Sci 119(Pt 21):4554-64 {{SGDpaper|S000119477}} PMID 17074835</ref><ref name='S000075799'>Shakoury-Elizeh M, et al. (2004) Transcriptional remodeling in response to iron deprivation in Saccharomyces cerevisiae. Mol Biol Cell 15(3):1233-43 {{SGDpaper|S000075799}} PMID 14668481</ref><ref name='S000053105'>Yamaguchi-Iwai Y, et al. (1996) Iron-regulated DNA binding by the AFT1 protein controls the iron regulon in yeast. EMBO J 15(13):3377-84 |
{{SGDpaper|S000053105}} PMID 8670839</ref> | {{SGDpaper|S000053105}} PMID 8670839</ref> | ||
<br> | <br> | ||
Latest revision as of 13:05, 13 February 2012
Share your knowledge...Edit this entry! <protect>
| Systematic name | YGL071W |
| Gene name | AFT1 |
| Aliases | RCS1 |
| Feature type | ORF, Verified |
| Coordinates | Chr VII:372012..374084 |
| Primary SGDID | S000003039 |
Description of YGL071W: Transcription factor involved in iron utilization and homeostasis; binds the consensus site PyPuCACCCPu and activates the expression of target genes in response to changes in iron availability; in iron-replete conditions activity is negatively regulated by Grx3p, Grx4p, and Fra2p, which regulate Aft1p translocation from the nucleus to the cytoplasm[1][2][3][4]
</protect>
Contents
Community Commentary
About Community Commentary. Please share your knowledge!
<protect>
References
See Help:References on how to add references
- ↑ Li H, et al. (2011) Histidine 103 in Fra2 Is an Iron-Sulfur Cluster Ligand in the [2Fe-2S] Fra2-Grx3 Complex and Is Required for in Vivo Iron Signaling in Yeast. J Biol Chem 286(1):867-76 SGD PMID 20978135
- ↑ Pujol-Carrion N, et al. (2006) Glutaredoxins Grx3 and Grx4 regulate nuclear localisation of Aft1 and the oxidative stress response in Saccharomyces cerevisiae. J Cell Sci 119(Pt 21):4554-64 SGD PMID 17074835
- ↑ Shakoury-Elizeh M, et al. (2004) Transcriptional remodeling in response to iron deprivation in Saccharomyces cerevisiae. Mol Biol Cell 15(3):1233-43 SGD PMID 14668481
- ↑ Yamaguchi-Iwai Y, et al. (1996) Iron-regulated DNA binding by the AFT1 protein controls the iron regulon in yeast. EMBO J 15(13):3377-84 SGD PMID 8670839
See Help:Categories on how to add the wiki page for this gene to a Category </protect>
