Difference between revisions of "YPL190C"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000006111 YPL190C] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''NAB3 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''NAB3 '' | ||
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
| − | |nowrap| Chr XVI: | + | |nowrap| Chr XVI:187725..185317 |
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| + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000006111 | ||
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| − | '''Description of | + | '''Description of YPL190C:''' RNA-binding protein, subunit of Nrd1 complex (Nrd1p-Nab3p-Sen1p); complex interacts with the exosome to mediate 3′ end formation of some mRNAs, snRNAs, snoRNAs, and CUTs; required for termination of non-poly(A) transcripts and efficient splicing<ref name='S000076765'>Carroll KL, et al. (2004) Identification of cis elements directing termination of yeast nonpolyadenylated snoRNA transcripts. Mol Cell Biol 24(14):6241-52 {{SGDpaper|S000076765}} PMID 15226427</ref><ref name='S000045868'>Conrad NK, et al. (2000) A yeast heterogeneous nuclear ribonucleoprotein complex associated with RNA polymerase II. Genetics 154(2):557-71 {{SGDpaper|S000045868}} PMID 10655211</ref><ref name='S000071624'>Steinmetz EJ, et al. (2001) RNA-binding protein Nrd1 directs poly(A)-independent 3'-end formation of RNA polymerase II transcripts. Nature 413(6853):327-31 {{SGDpaper|S000071624}} PMID 11565036</ref><ref name='S000039514'>Wilson SM, et al. (1994) Characterization of nuclear polyadenylated RNA-binding proteins in Saccharomyces cerevisiae. J Cell Biol 127(5):1173-84 |
{{SGDpaper|S000039514}} PMID 7962083</ref> | {{SGDpaper|S000039514}} PMID 7962083</ref> | ||
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==Community Commentary== | ==Community Commentary== | ||
{{CommentaryHelp}} | {{CommentaryHelp}} | ||
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| + | Specifically higher expression in carbon limited chemostat cultures versus carbon excess. | ||
| + | <ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. | ||
| + | J Biol Chem 278(5):3265-74</ref> | ||
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Latest revision as of 13:05, 10 May 2012
Share your knowledge...Edit this entry! <protect>
| Systematic name | YPL190C |
| Gene name | NAB3 |
| Aliases | HMD1 |
| Feature type | ORF, Verified |
| Coordinates | Chr XVI:187725..185317 |
| Primary SGDID | S000006111 |
Description of YPL190C: RNA-binding protein, subunit of Nrd1 complex (Nrd1p-Nab3p-Sen1p); complex interacts with the exosome to mediate 3′ end formation of some mRNAs, snRNAs, snoRNAs, and CUTs; required for termination of non-poly(A) transcripts and efficient splicing[1][2][3][4]
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Contents
Community Commentary
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References
See Help:References on how to add references
- ↑ Carroll KL, et al. (2004) Identification of cis elements directing termination of yeast nonpolyadenylated snoRNA transcripts. Mol Cell Biol 24(14):6241-52 SGD PMID 15226427
- ↑ Conrad NK, et al. (2000) A yeast heterogeneous nuclear ribonucleoprotein complex associated with RNA polymerase II. Genetics 154(2):557-71 SGD PMID 10655211
- ↑ Steinmetz EJ, et al. (2001) RNA-binding protein Nrd1 directs poly(A)-independent 3'-end formation of RNA polymerase II transcripts. Nature 413(6853):327-31 SGD PMID 11565036
- ↑ Wilson SM, et al. (1994) Characterization of nuclear polyadenylated RNA-binding proteins in Saccharomyces cerevisiae. J Cell Biol 127(5):1173-84 SGD PMID 7962083
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