Difference between revisions of "YLR057W"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000004047 YLR057W]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000004047 YLR057W]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''MNL2 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''MNL2 ''
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'''Description of YLR057W:''' Putative protein of unknown function; YLR050W is not an essential gene<ref name='S000071347'>Giaever G, et al. (2002) Functional profiling of the Saccharomyces cerevisiae genome. Nature 418(6896):387-91
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'''Description of YLR057W:''' Putative mannosidase involved in ER-associated protein degradation; localizes to the endoplasmic reticulum; sequence similarity with seven-hairpin glycosidase (GH47) family members, such as Mns1p and Mnl1p, that hydrolyze 1,2-linked alpha-D-mannose residues; non-essential gene<ref name='S000146979'>Benitez EM, et al. (2011) Mnl2, a novel component of the ER associated protein degradation pathway. Biochem Biophys Res Commun 414(3):528-32 {{SGDpaper|S000146979}} PMID 21971548</ref><ref name='S000071347'>Giaever G, et al. (2002) Functional profiling of the Saccharomyces cerevisiae genome. Nature 418(6896):387-91
 
  {{SGDpaper|S000071347}} PMID 12140549</ref>
 
  {{SGDpaper|S000071347}} PMID 12140549</ref>
 
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Latest revision as of 06:45, 23 January 2012

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Systematic name YLR057W
Gene name MNL2
Aliases
Feature type ORF, Verified
Coordinates Chr XII:255306..257855
Primary SGDID S000004047


Description of YLR057W: Putative mannosidase involved in ER-associated protein degradation; localizes to the endoplasmic reticulum; sequence similarity with seven-hairpin glycosidase (GH47) family members, such as Mns1p and Mnl1p, that hydrolyze 1,2-linked alpha-D-mannose residues; non-essential gene[1][2]




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References

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  1. Benitez EM, et al. (2011) Mnl2, a novel component of the ER associated protein degradation pathway. Biochem Biophys Res Commun 414(3):528-32 SGD PMID 21971548
  2. Giaever G, et al. (2002) Functional profiling of the Saccharomyces cerevisiae genome. Nature 418(6896):387-91 SGD PMID 12140549

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