Difference between revisions of "YOL081W"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000005441 YOL081W] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''IRA2 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''IRA2 '' | ||
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
|nowrap| Chr XV:171070..180309 | |nowrap| Chr XV:171070..180309 | ||
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| + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000005441 | ||
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<br> | <br> | ||
| − | '''Description of | + | '''Description of YOL081W:''' GTPase-activating protein that negatively regulates RAS by converting it from the GTP- to the GDP-bound inactive form, required for reducing cAMP levels under nutrient limiting conditions, has similarity to Ira1p and human neurofibromin<ref name='S000052853'>Gil R and Seeling JM (1999) Characterization of Saccharomyces cerevisiae strains expressing ira1 mutant alleles modeled after disease-causing mutations in NF1. Mol Cell Biochem 202(1-2):109-18 {{SGDpaper|S000052853}} PMID 10706001</ref><ref name='S000047724'>Tanaka K, et al. (1990) IRA2, a second gene of Saccharomyces cerevisiae that encodes a protein with a domain homologous to mammalian ras GTPase-activating protein. Mol Cell Biol 10(8):4303-13 |
{{SGDpaper|S000047724}} PMID 2164637</ref> | {{SGDpaper|S000047724}} PMID 2164637</ref> | ||
<br> | <br> | ||
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==Community Commentary== | ==Community Commentary== | ||
{{CommentaryHelp}} | {{CommentaryHelp}} | ||
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| + | <!-- PLEASE ADD Community Commentary ABOVE THIS MESSAGE. See below for an example of community annotation --> | ||
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| + | Specifically higher expression in carbon limited chemostat cultures versus carbon excess. | ||
| + | <ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. | ||
| + | J Biol Chem 278(5):3265-74</ref> | ||
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Latest revision as of 06:45, 23 January 2012
Share your knowledge...Edit this entry! <protect>
| Systematic name | YOL081W |
| Gene name | IRA2 |
| Aliases | CCS1, GLC4 |
| Feature type | ORF, Verified |
| Coordinates | Chr XV:171070..180309 |
| Primary SGDID | S000005441 |
Description of YOL081W: GTPase-activating protein that negatively regulates RAS by converting it from the GTP- to the GDP-bound inactive form, required for reducing cAMP levels under nutrient limiting conditions, has similarity to Ira1p and human neurofibromin[1][2]
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Contents
Community Commentary
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References
See Help:References on how to add references
- ↑ Gil R and Seeling JM (1999) Characterization of Saccharomyces cerevisiae strains expressing ira1 mutant alleles modeled after disease-causing mutations in NF1. Mol Cell Biochem 202(1-2):109-18 SGD PMID 10706001
- ↑ Tanaka K, et al. (1990) IRA2, a second gene of Saccharomyces cerevisiae that encodes a protein with a domain homologous to mammalian ras GTPase-activating protein. Mol Cell Biol 10(8):4303-13 SGD PMID 2164637
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