Difference between revisions of "YBR126C"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000000330 YBR126C] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''TPS1 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''TPS1 '' | ||
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
| − | |nowrap| Chr II: | + | |nowrap| Chr II:490392..488905 |
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| − | | | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000000330 |
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| − | '''Description of | + | '''Description of YBR126C:''' Synthase subunit of trehalose-6-P synthase/phosphatase complex; synthesizes the storage carbohydrate trehalose; also found in a monomeric form; expression is induced by the stress response and repressed by the Ras-cAMP pathway; protein abundance increases in response to DNA replication stress<ref name='S000044803'>Bell W, et al. (1992) Characterization of the 56-kDa subunit of yeast trehalose-6-phosphate synthase and cloning of its gene reveal its identity with the product of CIF1, a regulator of carbon catabolite inactivation. Eur J Biochem 209(3):951-9 {{SGDpaper|S000044803}} PMID 1425702</ref><ref name='S000053932'>Bell W, et al. (1998) Composition and functional analysis of the Saccharomyces cerevisiae trehalose synthase complex. J Biol Chem 273(50):33311-9 {{SGDpaper|S000053932}} PMID 9837904</ref><ref name='S000150401'>Tkach JM, et al. (2012) Dissecting DNA damage response pathways by analysing protein localization and abundance changes during DNA replication stress.LID - 10.1038/ncb2549 [doi] Nat Cell Biol () {{SGDpaper|S000150401}} PMID 22842922</ref><ref name='S000040969'>Winderickx J, et al. (1996) Regulation of genes encoding subunits of the trehalose synthase complex in Saccharomyces cerevisiae: novel variations of STRE-mediated transcription control? Mol Gen Genet 252(4):470-82 |
{{SGDpaper|S000040969}} PMID 8879249</ref> | {{SGDpaper|S000040969}} PMID 8879249</ref> | ||
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==Community Commentary== | ==Community Commentary== | ||
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| + | Specifically higher expression in carbon limited chemostat cultures versus carbon excess. | ||
| + | <ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. | ||
| + | J Biol Chem 278(5):3265-74</ref> | ||
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==References== | ==References== | ||
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Latest revision as of 13:05, 22 October 2012
Share your knowledge...Edit this entry! <protect>
| Systematic name | YBR126C |
| Gene name | TPS1 |
| Aliases | BYP1, CIF1, FDP1, GGS1, GLC6, TSS1 |
| Feature type | ORF, Verified |
| Coordinates | Chr II:490392..488905 |
| Primary SGDID | S000000330 |
Description of YBR126C: Synthase subunit of trehalose-6-P synthase/phosphatase complex; synthesizes the storage carbohydrate trehalose; also found in a monomeric form; expression is induced by the stress response and repressed by the Ras-cAMP pathway; protein abundance increases in response to DNA replication stress[1][2][3][4]
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Community Commentary
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References
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- ↑ Bell W, et al. (1992) Characterization of the 56-kDa subunit of yeast trehalose-6-phosphate synthase and cloning of its gene reveal its identity with the product of CIF1, a regulator of carbon catabolite inactivation. Eur J Biochem 209(3):951-9 SGD PMID 1425702
- ↑ Bell W, et al. (1998) Composition and functional analysis of the Saccharomyces cerevisiae trehalose synthase complex. J Biol Chem 273(50):33311-9 SGD PMID 9837904
- ↑ Tkach JM, et al. (2012) Dissecting DNA damage response pathways by analysing protein localization and abundance changes during DNA replication stress.LID - 10.1038/ncb2549 [doi] Nat Cell Biol () SGD PMID 22842922
- ↑ Winderickx J, et al. (1996) Regulation of genes encoding subunits of the trehalose synthase complex in Saccharomyces cerevisiae: novel variations of STRE-mediated transcription control? Mol Gen Genet 252(4):470-82 SGD PMID 8879249
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