Difference between revisions of "YML004C"
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− | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000004463 YML004C] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''GLO1 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''GLO1 '' | ||
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
|nowrap| Chr XIII:262685..261705 | |nowrap| Chr XIII:262685..261705 | ||
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+ | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000004463 | ||
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− | '''Description of | + | '''Description of YML004C:''' Monomeric glyoxalase I, catalyzes the detoxification of methylglyoxal (a by-product of glycolysis) via condensation with glutathione to produce S-D-lactoylglutathione; expression regulated by methylglyoxal levels and osmotic stress<ref name='S000075816'>Aguilera J and Prieto JA (2004) Yeast cells display a regulatory mechanism in response to methylglyoxal. FEMS Yeast Res 4(6):633-41 {{SGDpaper|S000075816}} PMID 15040952</ref><ref name='S000063316'>Frickel EM, et al. (2001) Yeast glyoxalase I is a monomeric enzyme with two active sites. J Biol Chem 276(3):1845-9 {{SGDpaper|S000063316}} PMID 11050082</ref><ref name='S000050684'>Inoue Y and Kimura A (1996) Identification of the structural gene for glyoxalase I from Saccharomyces cerevisiae. J Biol Chem 271(42):25958-65 {{SGDpaper|S000050684}} PMID 8824231</ref><ref name='S000049124'>Inoue Y, et al. (1998) Expression of the glyoxalase I gene of Saccharomyces cerevisiae is regulated by high osmolarity glycerol mitogen-activated protein kinase pathway in osmotic stress response. J Biol Chem 273(5):2977-83 |
{{SGDpaper|S000049124}} PMID 9446611</ref> | {{SGDpaper|S000049124}} PMID 9446611</ref> | ||
<br> | <br> | ||
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==Community Commentary== | ==Community Commentary== | ||
{{CommentaryHelp}} | {{CommentaryHelp}} | ||
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+ | Specifically higher expression in carbon limited chemostat cultures versus carbon excess. | ||
+ | <ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. | ||
+ | J Biol Chem 278(5):3265-74</ref> | ||
+ | --> | ||
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Latest revision as of 07:45, 23 January 2012
Share your knowledge...Edit this entry! <protect>
Systematic name | YML004C |
Gene name | GLO1 |
Aliases | |
Feature type | ORF, Verified |
Coordinates | Chr XIII:262685..261705 |
Primary SGDID | S000004463 |
Description of YML004C: Monomeric glyoxalase I, catalyzes the detoxification of methylglyoxal (a by-product of glycolysis) via condensation with glutathione to produce S-D-lactoylglutathione; expression regulated by methylglyoxal levels and osmotic stress[1][2][3][4]
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References
See Help:References on how to add references
- ↑ Aguilera J and Prieto JA (2004) Yeast cells display a regulatory mechanism in response to methylglyoxal. FEMS Yeast Res 4(6):633-41 SGD PMID 15040952
- ↑ Frickel EM, et al. (2001) Yeast glyoxalase I is a monomeric enzyme with two active sites. J Biol Chem 276(3):1845-9 SGD PMID 11050082
- ↑ Inoue Y and Kimura A (1996) Identification of the structural gene for glyoxalase I from Saccharomyces cerevisiae. J Biol Chem 271(42):25958-65 SGD PMID 8824231
- ↑ Inoue Y, et al. (1998) Expression of the glyoxalase I gene of Saccharomyces cerevisiae is regulated by high osmolarity glycerol mitogen-activated protein kinase pathway in osmotic stress response. J Biol Chem 273(5):2977-83 SGD PMID 9446611
See Help:Categories on how to add the wiki page for this gene to a Category </protect>