Difference between revisions of "YLR336C"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?locus=YLR336C YLR336C]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000004328 YLR336C]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''SGD1 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''SGD1 ''
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|nowrap| Chr XII:802396..799697
 
|nowrap| Chr XII:802396..799697
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000004328
 
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'''Description of {{PAGENAME}}:''' Essential nuclear protein with a possible role in the osmoregulatory glycerol response; interacts with phospholipase C (Plc1p); putative homolog of human NOM1 which is implicated in acute myeloid leukemia<ref name='S000080799'>Simmons HM, et al. (2005) Identification of NOM1, a nucleolar, eIF4A binding protein encoded within the chromosome 7q36 breakpoint region targeted in cases of pediatric acute myeloid leukemia. Gene 347(1):137-45 {{SGDpaper|S000080799}} PMID 15715967</ref><ref name='S000070006'>Lin H, et al. (2002) Phospholipase C interacts with Sgd1p and is required for expression of GPD1 and osmoresistance in Saccharomyces cerevisiae. Mol Genet Genomics 267(3):313-20 {{SGDpaper|S000070006}} PMID 12073033</ref><ref name='S000059303'>Akhtar N, et al. (2000) SGD1 encodes an essential nuclear protein of Saccharomyces cerevisiae that affects expression of the GPD1 gene for glycerol 3-phosphate dehydrogenase. FEBS Lett 483(2-3):87-92
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'''Description of YLR336C:''' Essential nuclear protein, required for biogenesis of the small ribosomal subunit; has a possible role in the osmoregulatory glycerol response; putative homolog of human NOM1 which is implicated in acute myeloid leukemia<ref name='S000059303'>Akhtar N, et al. (2000) SGD1 encodes an essential nuclear protein of Saccharomyces cerevisiae that affects expression of the GPD1 gene for glycerol 3-phosphate dehydrogenase. FEBS Lett 483(2-3):87-92 {{SGDpaper|S000059303}} PMID 11042259</ref><ref name='S000131880'>Li Z, et al. (2009) Rational extension of the ribosome biogenesis pathway using network-guided genetics. PLoS Biol 7(10):e1000213 {{SGDpaper|S000131880}} PMID 19806183</ref><ref name='S000070006'>Lin H, et al. (2002) Phospholipase C interacts with Sgd1p and is required for expression of GPD1 and osmoresistance in Saccharomyces cerevisiae. Mol Genet Genomics 267(3):313-20 {{SGDpaper|S000070006}} PMID 12073033</ref><ref name='S000080799'>Simmons HM, et al. (2005) Identification of NOM1, a nucleolar, eIF4A binding protein encoded within the chromosome 7q36 breakpoint region targeted in cases of pediatric acute myeloid leukemia. Gene 347(1):137-45
  {{SGDpaper|S000059303}} PMID 11042259</ref>
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  {{SGDpaper|S000080799}} PMID 15715967</ref>
 
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==Community Commentary==
 
==Community Commentary==
 
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<!-- PLEASE ADD Community Commentary ABOVE THIS MESSAGE. See below for an example of community annotation -->
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Specifically higher expression in carbon limited chemostat cultures versus carbon excess.
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<ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur.
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J Biol Chem 278(5):3265-74</ref>
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Latest revision as of 06:45, 23 January 2012

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Systematic name YLR336C
Gene name SGD1
Aliases
Feature type ORF, Verified
Coordinates Chr XII:802396..799697
Primary SGDID S000004328


Description of YLR336C: Essential nuclear protein, required for biogenesis of the small ribosomal subunit; has a possible role in the osmoregulatory glycerol response; putative homolog of human NOM1 which is implicated in acute myeloid leukemia[1][2][3][4]




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References

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  1. Akhtar N, et al. (2000) SGD1 encodes an essential nuclear protein of Saccharomyces cerevisiae that affects expression of the GPD1 gene for glycerol 3-phosphate dehydrogenase. FEBS Lett 483(2-3):87-92 SGD PMID 11042259
  2. Li Z, et al. (2009) Rational extension of the ribosome biogenesis pathway using network-guided genetics. PLoS Biol 7(10):e1000213 SGD PMID 19806183
  3. Lin H, et al. (2002) Phospholipase C interacts with Sgd1p and is required for expression of GPD1 and osmoresistance in Saccharomyces cerevisiae. Mol Genet Genomics 267(3):313-20 SGD PMID 12073033
  4. Simmons HM, et al. (2005) Identification of NOM1, a nucleolar, eIF4A binding protein encoded within the chromosome 7q36 breakpoint region targeted in cases of pediatric acute myeloid leukemia. Gene 347(1):137-45 SGD PMID 15715967

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