Difference between revisions of "YIL049W"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000001311 YIL049W] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''DFG10 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''DFG10 '' | ||
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
| − | |nowrap| Chr IX: | + | |nowrap| Chr IX:260158..260919 |
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| + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000001311 | ||
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<br> | <br> | ||
| − | '''Description of | + | '''Description of YIL049W:''' Probable polyprenol reductase that catalyzes conversion of polyprenol to dolichol, the precursor for N-glycosylation; involved in filamentous growth; mutations in human ortholog SRD5A3 confer CDG (Congenital Disorders of Glycosylation)<ref name='S000135785'>Cantagrel V, et al. (2010) SRD5A3 is required for converting polyprenol to dolichol and is mutated in a congenital glycosylation disorder. Cell 142(2):203-17 {{SGDpaper|S000135785}} PMID 20637498</ref><ref name='S000042772'>Mosch HU and Fink GR (1997) Dissection of filamentous growth by transposon mutagenesis in Saccharomyces cerevisiae. Genetics 145(3):671-84 |
{{SGDpaper|S000042772}} PMID 9055077</ref> | {{SGDpaper|S000042772}} PMID 9055077</ref> | ||
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==Community Commentary== | ==Community Commentary== | ||
{{CommentaryHelp}} | {{CommentaryHelp}} | ||
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| + | <!-- PLEASE ADD Community Commentary ABOVE THIS MESSAGE. See below for an example of community annotation --> | ||
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| + | Specifically higher expression in carbon limited chemostat cultures versus carbon excess. | ||
| + | <ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. | ||
| + | J Biol Chem 278(5):3265-74</ref> | ||
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Latest revision as of 06:45, 23 January 2012
Share your knowledge...Edit this entry! <protect>
| Systematic name | YIL049W |
| Gene name | DFG10 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr IX:260158..260919 |
| Primary SGDID | S000001311 |
Description of YIL049W: Probable polyprenol reductase that catalyzes conversion of polyprenol to dolichol, the precursor for N-glycosylation; involved in filamentous growth; mutations in human ortholog SRD5A3 confer CDG (Congenital Disorders of Glycosylation)[1][2]
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Community Commentary
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References
See Help:References on how to add references
- ↑ Cantagrel V, et al. (2010) SRD5A3 is required for converting polyprenol to dolichol and is mutated in a congenital glycosylation disorder. Cell 142(2):203-17 SGD PMID 20637498
- ↑ Mosch HU and Fink GR (1997) Dissection of filamentous growth by transposon mutagenesis in Saccharomyces cerevisiae. Genetics 145(3):671-84 SGD PMID 9055077
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