Difference between revisions of "YPR019W"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000006223 YPR019W]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000006223 YPR019W]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''MCM4 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''MCM4 ''

Latest revision as of 06:45, 23 January 2012

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Systematic name YPR019W
Gene name MCM4
Aliases CDC54, HCD21
Feature type ORF, Verified
Coordinates Chr XVI:596750..599551
Primary SGDID S000006223


Description of YPR019W: Essential helicase component of heterohexameric MCM2-7 complexes which bind pre-replication complexes on DNA and melt DNA prior to replication; forms an Mcm4p-6p-7p subcomplex; shows nuclear accumulation in G1; homolog of S. pombe Cdc21p[1][2][3]




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References

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  1. Ma X, et al. (2010) The effects of oligomerization on Saccharomyces cerevisiae Mcm4/6/7 function. BMC Biochem 11():37 SGD PMID 20860810
  2. Tanaka S and Diffley JF (2002) Interdependent nuclear accumulation of budding yeast Cdt1 and Mcm2-7 during G1 phase. Nat Cell Biol 4(3):198-207 SGD PMID 11836525
  3. Tye BK (1999) MCM proteins in DNA replication. Annu Rev Biochem 68:649-86 SGD PMID 10872463

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