Difference between revisions of "YGR175C"
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{|{{Prettytable}} align = 'right' width = '200px' | {|{{Prettytable}} align = 'right' width = '200px' | ||
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− | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000003407 YGR175C] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''ERG1 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''ERG1 '' | ||
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
− | |nowrap| Chr VII: | + | |nowrap| Chr VII:848423..846933 |
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+ | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000003407 | ||
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− | '''Description of | + | '''Description of YGR175C:''' Squalene epoxidase, catalyzes the epoxidation of squalene to 2,3-oxidosqualene; plays an essential role in the ergosterol-biosynthesis pathway and is the specific target of the antifungal drug terbinafine<ref name='S000046115'>Jandrositz A, et al. (1991) The gene encoding squalene epoxidase from Saccharomyces cerevisiae: cloning and characterization. Gene 107(1):155-60 {{SGDpaper|S000046115}} PMID 1743514</ref><ref name='S000057708'>Satoh T, et al. (1993) Enzymatic properties of squalene epoxidase from Saccharomyces cerevisiae. Biol Pharm Bull 16(4):349-52 |
− | {{SGDpaper| | + | {{SGDpaper|S000057708}} PMID 8358382</ref> |
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<br> | <br> | ||
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==Community Commentary== | ==Community Commentary== | ||
{{CommentaryHelp}} | {{CommentaryHelp}} | ||
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+ | <!-- PLEASE ADD Community Commentary ABOVE THIS MESSAGE. See below for an example of community annotation --> | ||
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+ | Specifically higher expression in carbon limited chemostat cultures versus carbon excess. | ||
+ | <ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. | ||
+ | J Biol Chem 278(5):3265-74</ref> | ||
+ | --> | ||
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Latest revision as of 07:45, 23 January 2012
Share your knowledge...Edit this entry! <protect>
Systematic name | YGR175C |
Gene name | ERG1 |
Aliases | |
Feature type | ORF, Verified |
Coordinates | Chr VII:848423..846933 |
Primary SGDID | S000003407 |
Description of YGR175C: Squalene epoxidase, catalyzes the epoxidation of squalene to 2,3-oxidosqualene; plays an essential role in the ergosterol-biosynthesis pathway and is the specific target of the antifungal drug terbinafine[1][2]
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Contents
Community Commentary
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References
See Help:References on how to add references
- ↑ Jandrositz A, et al. (1991) The gene encoding squalene epoxidase from Saccharomyces cerevisiae: cloning and characterization. Gene 107(1):155-60 SGD PMID 1743514
- ↑ Satoh T, et al. (1993) Enzymatic properties of squalene epoxidase from Saccharomyces cerevisiae. Biol Pharm Bull 16(4):349-52 SGD PMID 8358382
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