Difference between revisions of "YGL251C"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?locus=YGL251C YGL251C]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000003220 YGL251C]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''HFM1 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''HFM1 ''
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|nowrap| Chr VII:31636..27921
 
|nowrap| Chr VII:31636..27921
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000003220
 
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'''Description of {{PAGENAME}}:''' Meiosis specific DNA helicase involved in the conversion of double-stranded breaks to later recombination intermediates and in crossover control; catalyzes the unwinding of Holliday junctions; has ssDNA and dsDNA stimulated ATPase activity<ref name='S000070274'>Nakagawa T and Kolodner RD (2002) The MER3 DNA helicase catalyzes the unwinding of holliday junctions. J Biol Chem 277(31):28019-24 {{SGDpaper|S000070274}} PMID 12039965</ref><ref name='S000069901'>Nakagawa T and Kolodner RD (2002) Saccharomyces cerevisiae Mer3 is a DNA helicase involved in meiotic crossing over. Mol Cell Biol 22(10):3281-91 {{SGDpaper|S000069901}} PMID 11971962</ref><ref name='S000061281'>Nakagawa T, et al. (2001) The MER3 helicase involved in meiotic crossing over is stimulated by single-stranded DNA-binding proteins and unwinds DNA in the 3' to 5' direction. J Biol Chem 276(34):31487-93 {{SGDpaper|S000061281}} PMID 11376001</ref><ref name='S000053918'>Coissac E, et al. (1996) Sequence of a 39,411 bp DNA fragment covering the left end of chromosome VII of Saccharomyces cerevisiae. Yeast 12(15):1555-62
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'''Description of YGL251C:''' Meiosis specific DNA helicase involved in the conversion of double-stranded breaks to later recombination intermediates and in crossover control; catalyzes the unwinding of Holliday junctions; has ssDNA and dsDNA stimulated ATPase activity<ref name='S000053918'>Coissac E, et al. (1996) Sequence of a 39,411 bp DNA fragment covering the left end of chromosome VII of Saccharomyces cerevisiae. Yeast 12(15):1555-62 {{SGDpaper|S000053918}} PMID 8972578</ref><ref name='S000069901'>Nakagawa T and Kolodner RD (2002) Saccharomyces cerevisiae Mer3 is a DNA helicase involved in meiotic crossing over. Mol Cell Biol 22(10):3281-91 {{SGDpaper|S000069901}} PMID 11971962</ref><ref name='S000070274'>Nakagawa T and Kolodner RD (2002) The MER3 DNA helicase catalyzes the unwinding of holliday junctions. J Biol Chem 277(31):28019-24 {{SGDpaper|S000070274}} PMID 12039965</ref><ref name='S000061281'>Nakagawa T, et al. (2001) The MER3 helicase involved in meiotic crossing over is stimulated by single-stranded DNA-binding proteins and unwinds DNA in the 3' to 5' direction. J Biol Chem 276(34):31487-93
{{SGDpaper|S000053918}} PMID 8972578</ref>
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{{SGDpaper|S000061281}} PMID 11376001</ref>
 
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==Community Commentary==
 
==Community Commentary==
 
{{CommentaryHelp}}
 
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<!-- PLEASE ADD Community Commentary ABOVE THIS MESSAGE. See below for an example of community annotation -->
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Specifically higher expression in carbon limited chemostat cultures versus carbon excess.
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<ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur.
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J Biol Chem 278(5):3265-74</ref>
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Latest revision as of 07:45, 23 January 2012

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Systematic name YGL251C
Gene name HFM1
Aliases MER3
Feature type ORF, Verified
Coordinates Chr VII:31636..27921
Primary SGDID S000003220


Description of YGL251C: Meiosis specific DNA helicase involved in the conversion of double-stranded breaks to later recombination intermediates and in crossover control; catalyzes the unwinding of Holliday junctions; has ssDNA and dsDNA stimulated ATPase activity[1][2][3][4]




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References

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  1. Coissac E, et al. (1996) Sequence of a 39,411 bp DNA fragment covering the left end of chromosome VII of Saccharomyces cerevisiae. Yeast 12(15):1555-62 SGD PMID 8972578
  2. Nakagawa T and Kolodner RD (2002) Saccharomyces cerevisiae Mer3 is a DNA helicase involved in meiotic crossing over. Mol Cell Biol 22(10):3281-91 SGD PMID 11971962
  3. Nakagawa T and Kolodner RD (2002) The MER3 DNA helicase catalyzes the unwinding of holliday junctions. J Biol Chem 277(31):28019-24 SGD PMID 12039965
  4. Nakagawa T, et al. (2001) The MER3 helicase involved in meiotic crossing over is stimulated by single-stranded DNA-binding proteins and unwinds DNA in the 3' to 5' direction. J Biol Chem 276(34):31487-93 SGD PMID 11376001

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