Difference between revisions of "YGL171W"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?locus=YGL171W YGL171W]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000003139 YGL171W]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''ROK1 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''ROK1 ''
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
|nowrap| Chr VII:182396..184090
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|nowrap| Chr VII:182390..184084
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000003139
 
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'''Description of {{PAGENAME}}:''' ATP-dependent RNA helicase of the DEAD box family; required for 18S rRNA synthesis<ref name='S000058443'>Venema J and Tollervey D (1999) Ribosome synthesis in Saccharomyces cerevisiae. Annu Rev Genet 33():261-311 {{SGDpaper|S000058443}} PMID 10690410</ref><ref name='S000051998'>Oh JY and Kim J (1999) ATP hydrolysis activity of the DEAD box protein Rok1p is required for in vivo ROK1 function. Nucleic Acids Res 27(13):2753-9
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'''Description of YGL171W:''' RNA-dependent ATPase; involved in pre-rRNA processing at sites A0, A1, and A2, and in control of cell cycle progression; contains two upstream open reading frames (uORFs) in 5' untranslated region which regulate translation<ref name='S000128212'>Garcia I and Uhlenbeck OC (2008) Differential RNA-Dependent ATPase Activities of Four rRNA Processing Yeast DEAD-Box Proteins (dagger). Biochemistry 47(47):12562-73 {{SGDpaper|S000128212}} PMID 18975973</ref><ref name='S000139084'>Jeon S and Kim J (2010) Upstream open reading frames regulate the cell cycle-dependent expression of the RNA helicase Rok1 in Saccharomyces cerevisiae. FEBS Lett 584(22):4593-8 {{SGDpaper|S000139084}} PMID 20969870</ref><ref name='S000051145'>Venema J, et al. (1997) Rok1p is a putative RNA helicase required for rRNA processing. Mol Cell Biol 17(6):3398-407
  {{SGDpaper|S000051998}} PMID 10373593</ref>
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  {{SGDpaper|S000051145}} PMID 9154839</ref>
 
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==Community Commentary==
 
==Community Commentary==
 
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<!-- PLEASE ADD Community Commentary ABOVE THIS MESSAGE. See below for an example of community annotation -->
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Specifically higher expression in carbon limited chemostat cultures versus carbon excess.
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<ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur.
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J Biol Chem 278(5):3265-74</ref>
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Latest revision as of 13:05, 26 April 2012

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Systematic name YGL171W
Gene name ROK1
Aliases
Feature type ORF, Verified
Coordinates Chr VII:182390..184084
Primary SGDID S000003139


Description of YGL171W: RNA-dependent ATPase; involved in pre-rRNA processing at sites A0, A1, and A2, and in control of cell cycle progression; contains two upstream open reading frames (uORFs) in 5' untranslated region which regulate translation[1][2][3]




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References

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  1. Garcia I and Uhlenbeck OC (2008) Differential RNA-Dependent ATPase Activities of Four rRNA Processing Yeast DEAD-Box Proteins (dagger). Biochemistry 47(47):12562-73 SGD PMID 18975973
  2. Jeon S and Kim J (2010) Upstream open reading frames regulate the cell cycle-dependent expression of the RNA helicase Rok1 in Saccharomyces cerevisiae. FEBS Lett 584(22):4593-8 SGD PMID 20969870
  3. Venema J, et al. (1997) Rok1p is a putative RNA helicase required for rRNA processing. Mol Cell Biol 17(6):3398-407 SGD PMID 9154839

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