Difference between revisions of "YPL098C"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000006019 YPL098C] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''MGR2 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''MGR2 '' | ||
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| − | '''Description of YPL098C:''' | + | '''Description of YPL098C:''' Subunit of the TIM23 translocase complex; acts to couple Tim21p with the core Tim23 translocase; absolutely required for mitochondrial import of presequence-containing proteins at elevated temperature; required for viability of cells lacking the mitochondrial genome (petite-negative phenotype)<ref name='S000113568'>Dunn CD, et al. (2006) A genomewide screen for petite-negative yeast strains yields a new subunit of the i-AAA protease complex. Mol Biol Cell 17(1):213-26 {{SGDpaper|S000113568}} PMID 16267274</ref><ref name='S000149564'>Gebert M, et al. (2012) Mgr2 promotes coupling of the mitochondrial presequence translocase to partner complexes. J Cell Biol 197(5):595-604 |
| − | {{SGDpaper| | + | {{SGDpaper|S000149564}} PMID 22613836</ref> |
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Latest revision as of 14:05, 7 June 2012
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| Systematic name | YPL098C |
| Gene name | MGR2 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr XVI:364727..364386 |
| Primary SGDID | S000006019 |
Description of YPL098C: Subunit of the TIM23 translocase complex; acts to couple Tim21p with the core Tim23 translocase; absolutely required for mitochondrial import of presequence-containing proteins at elevated temperature; required for viability of cells lacking the mitochondrial genome (petite-negative phenotype)[1][2]
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References
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- ↑ Dunn CD, et al. (2006) A genomewide screen for petite-negative yeast strains yields a new subunit of the i-AAA protease complex. Mol Biol Cell 17(1):213-26 SGD PMID 16267274
- ↑ Gebert M, et al. (2012) Mgr2 promotes coupling of the mitochondrial presequence translocase to partner complexes. J Cell Biol 197(5):595-604 SGD PMID 22613836
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