Difference between revisions of "YOR178C"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000005704 YOR178C]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000005704 YOR178C]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''GAC1 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''GAC1 ''

Latest revision as of 06:45, 23 January 2012

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Systematic name YOR178C
Gene name GAC1
Aliases
Feature type ORF, Verified
Coordinates Chr XV:670241..667860
Primary SGDID S000005704


Description of YOR178C: Regulatory subunit for Glc7p type-1 protein phosphatase (PP1), tethers Glc7p to Gsy2p glycogen synthase, binds Hsf1p heat shock transcription factor, required for induction of some HSF-regulated genes under heat shock[1][2][3][4]




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Protein Details

Protein Modification

Modification(s): Phosphorylation

Identified as an efficient substrate of Clb2-Cdk1-as1 in a screen of a proteomic GST-fusion library. [2] [5]





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References

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  1. Nigavekar SS, et al. (2002) Glc8 is a glucose-repressible activator of Glc7 protein phosphatase-1. Arch Biochem Biophys 404(1):71-9 SGD PMID 12127071
  2. 2.0 2.1 Ubersax JA, et al. (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64 SGD PMID 14574415
  3. Williams-Hart T, et al. (2002) Protein phosphatase type 1 regulates ion homeostasis in Saccharomyces cerevisiae. Genetics 160(4):1423-37 SGD PMID 11973298
  4. Wu X, et al. (2001) Characterization of Gac1p, a regulatory subunit of protein phosphatase type I involved in glycogen accumulation in Saccharomyces cerevisiae. Mol Genet Genomics 265(4):622-35 SGD PMID 11459182
  5. submitted by Jeff Ubersax on 2004-01-29

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