Difference between revisions of "YOR165W"
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− | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000005691 YOR165W] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''SEY1 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''SEY1 '' | ||
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− | '''Description of YOR165W:''' GTPase | + | '''Description of YOR165W:''' Dynamin-like GTPase that mediates homotypic ER fusion; has a role in ER morphology; interacts physically and genetically with Yop1p and Rtn1p; functional ortholog of the human atlastin ATL1, defects in which cause a form of the human disease hereditary spastic paraplegia; homolog of Arabidopsis RHD3<ref name='S000149156'>Anwar K, et al. (2012) The dynamin-like GTPase Sey1p mediates homotypic ER fusion in S. cerevisiae. J Cell Biol 197(2):209-17 {{SGDpaper|S000149156}} PMID 22508509</ref><ref name='S000071802'>Brands A and Ho TH (2002) Function of a plant stress-induced gene, HVA22. Synthetic enhancement screen with its yeast homolog reveals its role in vesicular traffic. Plant Physiol 130(3):1121-31 {{SGDpaper|S000071802}} PMID 12427979</ref><ref name='S000131190'>Hu J, et al. (2009) A class of dynamin-like GTPases involved in the generation of the tubular ER network. Cell 138(3):549-61 |
{{SGDpaper|S000131190}} PMID 19665976</ref> | {{SGDpaper|S000131190}} PMID 19665976</ref> | ||
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Latest revision as of 14:05, 9 May 2012
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Systematic name | YOR165W |
Gene name | SEY1 |
Aliases | |
Feature type | ORF, Verified |
Coordinates | Chr XV:644566..646896 |
Primary SGDID | S000005691 |
Description of YOR165W: Dynamin-like GTPase that mediates homotypic ER fusion; has a role in ER morphology; interacts physically and genetically with Yop1p and Rtn1p; functional ortholog of the human atlastin ATL1, defects in which cause a form of the human disease hereditary spastic paraplegia; homolog of Arabidopsis RHD3[1][2][3]
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References
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- ↑ Anwar K, et al. (2012) The dynamin-like GTPase Sey1p mediates homotypic ER fusion in S. cerevisiae. J Cell Biol 197(2):209-17 SGD PMID 22508509
- ↑ Brands A and Ho TH (2002) Function of a plant stress-induced gene, HVA22. Synthetic enhancement screen with its yeast homolog reveals its role in vesicular traffic. Plant Physiol 130(3):1121-31 SGD PMID 12427979
- ↑ Hu J, et al. (2009) A class of dynamin-like GTPases involved in the generation of the tubular ER network. Cell 138(3):549-61 SGD PMID 19665976
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