Difference between revisions of "YHR099W"
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− | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000001141 YHR099W] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''TRA1 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''TRA1 '' |
Latest revision as of 06:45, 23 January 2012
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Systematic name | YHR099W |
Gene name | TRA1 |
Aliases | |
Feature type | ORF, Verified |
Coordinates | Chr VIII:302761..313995 |
Primary SGDID | S000001141 |
Description of YHR099W: Subunit of SAGA and NuA4 histone acetyltransferase complexes; interacts with acidic activators (e.g., Gal4p) which leads to transcription activation; similar to human TRRAP, which is a cofactor for c-Myc mediated oncogenic transformation[1][2][3][4]
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Contents
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References
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- ↑ Bhaumik SR, et al. (2004) In vivo target of a transcriptional activator revealed by fluorescence resonance energy transfer. Genes Dev 18(3):333-43 SGD PMID 14871930
- ↑ Brown CE, et al. (2001) Recruitment of HAT complexes by direct activator interactions with the ATM-related Tra1 subunit. Science 292(5525):2333-7 SGD PMID 11423663
- ↑ Grant PA, et al. (1998) The ATM-related cofactor Tra1 is a component of the purified SAGA complex. Mol Cell 2(6):863-7 SGD PMID 9885573
- ↑ Saleh A, et al. (1998) Tra1p is a component of the yeast Ada.Spt transcriptional regulatory complexes. J Biol Chem 273(41):26559-65 SGD PMID 9756893
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