Difference between revisions of "YBR263W"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000000467 YBR263W]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000000467 YBR263W]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''SHM1 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''SHM1 ''

Latest revision as of 06:45, 23 January 2012

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Systematic name YBR263W
Gene name SHM1
Aliases SHMT1, TMP3
Feature type ORF, Verified
Coordinates Chr II:736264..737736
Primary SGDID S000000467


Description of YBR263W: Mitochondrial serine hydroxymethyltransferase, converts serine to glycine plus 5,10 methylenetetrahydrofolate; involved in generating precursors for purine, pyrimidine, amino acid, and lipid biosynthesis; reverse reaction generates serine[1][2][3]




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References

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  1. Kastanos EK, et al. (1997) Role of mitochondrial and cytoplasmic serine hydroxymethyltransferase isozymes in de novo purine synthesis in Saccharomyces cerevisiae. Biochemistry 36(48):14956-64 SGD PMID 9398220
  2. McNeil JB, et al. (1994) Cloning and molecular characterization of three genes, including two genes encoding serine hydroxymethyltransferases, whose inactivation is required to render yeast auxotrophic for glycine. J Biol Chem 269(12):9155-65 SGD PMID 8132653
  3. Taylor BV, et al. (1993) Cloning of the genes encoding the serine hydroxymethyltransferases from Saccharomyces cerevisiae. Adv Exp Med Biol 338:711-4 SGD PMID 8304212

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