Difference between revisions of "YEL032W"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?locus=YEL032W YEL032W]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000000758 YEL032W]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''MCM3 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''MCM3 ''
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|nowrap| Chr V:86937..89852
 
|nowrap| Chr V:86937..89852
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000000758
 
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'''Description of {{PAGENAME}}:''' Protein involved in DNA replication; component of the Mcm2-7 hexameric complex that binds chromatin as a part of the pre-replicative complex<ref name='S000054742'>Yan H, et al. (1991) Mcm2 and Mcm3, two proteins important for ARS activity, are related in structure and function. Genes Dev 5(6):944-57 {{SGDpaper|S000054742}} PMID 2044961</ref><ref name='S000046283'>Whitebread LA and Dalton S (1995) Cdc54 belongs to the Cdc46/Mcm3 family of proteins which are essential for initiation of eukaryotic DNA replication. Gene 155(1):113-7 {{SGDpaper|S000046283}} PMID 7698653</ref><ref name='S000040243'>Homesley L, et al. (2000) Mcm10 and the MCM2-7 complex interact to initiate DNA synthesis and to release replication factors from origins. Genes Dev 14(8):913-26
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'''Description of YEL032W:''' Protein involved in DNA replication; component of the Mcm2-7 hexameric complex that binds chromatin as a part of the pre-replicative complex<ref name='S000040243'>Homesley L, et al. (2000) Mcm10 and the MCM2-7 complex interact to initiate DNA synthesis and to release replication factors from origins. Genes Dev 14(8):913-26 {{SGDpaper|S000040243}} PMID 10783164</ref><ref name='S000046283'>Whitebread LA and Dalton S (1995) Cdc54 belongs to the Cdc46/Mcm3 family of proteins which are essential for initiation of eukaryotic DNA replication. Gene 155(1):113-7 {{SGDpaper|S000046283}} PMID 7698653</ref><ref name='S000054742'>Yan H, et al. (1991) Mcm2 and Mcm3, two proteins important for ARS activity, are related in structure and function. Genes Dev 5(6):944-57
  {{SGDpaper|S000040243}} PMID 10783164</ref>
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  {{SGDpaper|S000054742}} PMID 2044961</ref>
 
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<!-- PLEASE ADD Community Commentary ABOVE THIS MESSAGE. See below for an example of community annotation -->
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Specifically higher expression in carbon limited chemostat cultures versus carbon excess.
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<ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur.
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J Biol Chem 278(5):3265-74</ref>
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Latest revision as of 06:45, 23 January 2012

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Systematic name YEL032W
Gene name MCM3
Aliases
Feature type ORF, Verified
Coordinates Chr V:86937..89852
Primary SGDID S000000758


Description of YEL032W: Protein involved in DNA replication; component of the Mcm2-7 hexameric complex that binds chromatin as a part of the pre-replicative complex[1][2][3]




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Community Commentary

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Protein Details

Protein Modification

Modification(s): Phosphorylation

Identified as an efficient substrate of Clb2-Cdk1-as1 in a screen of a proteomic GST-fusion library. [4] [5]





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References

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  1. Homesley L, et al. (2000) Mcm10 and the MCM2-7 complex interact to initiate DNA synthesis and to release replication factors from origins. Genes Dev 14(8):913-26 SGD PMID 10783164
  2. Whitebread LA and Dalton S (1995) Cdc54 belongs to the Cdc46/Mcm3 family of proteins which are essential for initiation of eukaryotic DNA replication. Gene 155(1):113-7 SGD PMID 7698653
  3. Yan H, et al. (1991) Mcm2 and Mcm3, two proteins important for ARS activity, are related in structure and function. Genes Dev 5(6):944-57 SGD PMID 2044961
  4. Ubersax JA, et al. (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64 SGD PMID 14574415
  5. submitted by Jeff Ubersax on 2004-01-27

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