Difference between revisions of "YDL028C"
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{|{{Prettytable}} align = 'right' width = '200px' | {|{{Prettytable}} align = 'right' width = '200px' | ||
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− | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000002186 YDL028C] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''MPS1 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''MPS1 '' | ||
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
− | |nowrap| Chr IV: | + | |nowrap| Chr IV:403291..400997 |
+ | |- | ||
+ | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000002186 | ||
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− | '''Description of | + | '''Description of YDL028C:''' Dual-specificity kinase required for spindle pole body (SPB) duplication and spindle checkpoint function; substrates include SPB proteins Spc42p, Spc110p, and Spc98p, mitotic exit network protein Mob1p, and checkpoint protein Mad1p<ref name='S000069129'>Castillo AR, et al. (2002) The yeast protein kinase Mps1p is required for assembly of the integral spindle pole body component Spc42p. J Cell Biol 156(3):453-65 {{SGDpaper|S000069129}} PMID 11827982</ref><ref name='S000060774'>Friedman DB, et al. (2001) Yeast Mps1p phosphorylates the spindle pole component Spc110p in the N-terminal domain. J Biol Chem 276(21):17958-67 {{SGDpaper|S000060774}} PMID 11278681</ref><ref name='S000047902'>Hardwick KG, et al. (1996) Activation of the budding yeast spindle assembly checkpoint without mitotic spindle disruption. Science 273(5277):953-6 {{SGDpaper|S000047902}} PMID 8688079</ref><ref name='S000044607'>Lauze E, et al. (1995) Yeast spindle pole body duplication gene MPS1 encodes an essential dual specificity protein kinase. EMBO J 14(8):1655-63 {{SGDpaper|S000044607}} PMID 7737118</ref><ref name='S000047704'>Luca FC and Winey M (1998) MOB1, an essential yeast gene required for completion of mitosis and maintenance of ploidy. Mol Biol Cell 9(1):29-46 |
− | + | {{SGDpaper|S000047704}} PMID 9436989</ref> | |
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==Community Commentary== | ==Community Commentary== | ||
{{CommentaryHelp}} | {{CommentaryHelp}} | ||
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+ | <!-- PLEASE ADD Community Commentary ABOVE THIS MESSAGE. See below for an example of community annotation --> | ||
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+ | Specifically higher expression in carbon limited chemostat cultures versus carbon excess. | ||
+ | <ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. | ||
+ | J Biol Chem 278(5):3265-74</ref> | ||
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Latest revision as of 06:45, 23 January 2012
Share your knowledge...Edit this entry! <protect>
Systematic name | YDL028C |
Gene name | MPS1 |
Aliases | RPK1 |
Feature type | ORF, Verified |
Coordinates | Chr IV:403291..400997 |
Primary SGDID | S000002186 |
Description of YDL028C: Dual-specificity kinase required for spindle pole body (SPB) duplication and spindle checkpoint function; substrates include SPB proteins Spc42p, Spc110p, and Spc98p, mitotic exit network protein Mob1p, and checkpoint protein Mad1p[1][2][3][4][5]
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Contents
Community Commentary
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References
See Help:References on how to add references
- ↑ Castillo AR, et al. (2002) The yeast protein kinase Mps1p is required for assembly of the integral spindle pole body component Spc42p. J Cell Biol 156(3):453-65 SGD PMID 11827982
- ↑ Friedman DB, et al. (2001) Yeast Mps1p phosphorylates the spindle pole component Spc110p in the N-terminal domain. J Biol Chem 276(21):17958-67 SGD PMID 11278681
- ↑ Hardwick KG, et al. (1996) Activation of the budding yeast spindle assembly checkpoint without mitotic spindle disruption. Science 273(5277):953-6 SGD PMID 8688079
- ↑ Lauze E, et al. (1995) Yeast spindle pole body duplication gene MPS1 encodes an essential dual specificity protein kinase. EMBO J 14(8):1655-63 SGD PMID 7737118
- ↑ Luca FC and Winey M (1998) MOB1, an essential yeast gene required for completion of mitosis and maintenance of ploidy. Mol Biol Cell 9(1):29-46 SGD PMID 9436989
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