Difference between revisions of "YBR089C-A"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000002157 YBR089C-A] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''NHP6B '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''NHP6B '' | ||
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
| − | |nowrap| Chr II: | + | |nowrap| Chr II:426489..426190 |
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| + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000002157 | ||
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| − | '''Description of | + | '''Description of YBR089C-A:''' High-mobility group (HMG) protein that binds to and remodels nucleosomes; involved in recruiting FACT and other chromatin remodelling complexes to the chromosomes; functionally redundant with Nhp6Ap; homologous to mammalian HMGB1 and HMGB2<ref name='S000052961'>Paull TT, et al. (1996) Yeast HMG proteins NHP6A/B potentiate promoter-specific transcriptional activation in vivo and assembly of preinitiation complexes in vitro. Genes Dev 10(21):2769-81 {{SGDpaper|S000052961}} PMID 8946917</ref><ref name='S000076495'>Rhoades AR, et al. (2004) Structural features of nucleosomes reorganized by yeast FACT and its HMG box component, Nhp6. Mol Cell Biol 24(9):3907-17 {{SGDpaper|S000076495}} PMID 15082784</ref><ref name='S000133004'>Stillman DJ (2010) Nhp6: A small but powerful effector of chromatin structure in Saccharomyces cerevisiae. Biochim Biophys Acta 1799(1-2):175-180 {{SGDpaper|S000133004}} PMID 20123079</ref><ref name='S000133511'>Thomas JO (2001) HMG1 and 2: architectural DNA-binding proteins. Biochem Soc Trans 29(Pt 4):395-401 {{SGDpaper|S000133511}} PMID 11497996</ref><ref name='S000131309'>Xin H, et al. (2009) yFACT induces global accessibility of nucleosomal DNA without H2A-H2B displacement. Mol Cell 35(3):365-76 |
| − | {{SGDpaper| | + | {{SGDpaper|S000131309}} PMID 19683499</ref> |
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==Community Commentary== | ==Community Commentary== | ||
{{CommentaryHelp}} | {{CommentaryHelp}} | ||
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| + | <!-- PLEASE ADD Community Commentary ABOVE THIS MESSAGE. See below for an example of community annotation --> | ||
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| + | Specifically higher expression in carbon limited chemostat cultures versus carbon excess. | ||
| + | <ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. | ||
| + | J Biol Chem 278(5):3265-74</ref> | ||
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Latest revision as of 06:45, 23 January 2012
Share your knowledge...Edit this entry! <protect>
| Systematic name | YBR089C-A |
| Gene name | NHP6B |
| Aliases | YBR090C-A |
| Feature type | ORF, Verified |
| Coordinates | Chr II:426489..426190 |
| Primary SGDID | S000002157 |
Description of YBR089C-A: High-mobility group (HMG) protein that binds to and remodels nucleosomes; involved in recruiting FACT and other chromatin remodelling complexes to the chromosomes; functionally redundant with Nhp6Ap; homologous to mammalian HMGB1 and HMGB2[1][2][3][4][5]
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References
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- ↑ Paull TT, et al. (1996) Yeast HMG proteins NHP6A/B potentiate promoter-specific transcriptional activation in vivo and assembly of preinitiation complexes in vitro. Genes Dev 10(21):2769-81 SGD PMID 8946917
- ↑ Rhoades AR, et al. (2004) Structural features of nucleosomes reorganized by yeast FACT and its HMG box component, Nhp6. Mol Cell Biol 24(9):3907-17 SGD PMID 15082784
- ↑ Stillman DJ (2010) Nhp6: A small but powerful effector of chromatin structure in Saccharomyces cerevisiae. Biochim Biophys Acta 1799(1-2):175-180 SGD PMID 20123079
- ↑ Thomas JO (2001) HMG1 and 2: architectural DNA-binding proteins. Biochem Soc Trans 29(Pt 4):395-401 SGD PMID 11497996
- ↑ Xin H, et al. (2009) yFACT induces global accessibility of nucleosomal DNA without H2A-H2B displacement. Mol Cell 35(3):365-76 SGD PMID 19683499
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