Difference between revisions of "YPR129W"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000006333 YPR129W] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''SCD6 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''SCD6 '' | ||
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
| − | |nowrap| Chr XVI: | + | |nowrap| Chr XVI:792687..793736 |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000006333 | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000006333 | ||
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| − | '''Description of YPR129W:''' | + | '''Description of YPR129W:''' Repressor of translation initiation; binds eIF4G through its RGG domain and inhibits recruitment of the preinitiation complex; also contains an Lsm domain; may have a role in RNA processing; overproduction suppresses null mutation in clathrin heavy chain gene CHC1<ref name='S000076596'>Albrecht M and Lengauer T (2004) Novel Sm-like proteins with long C-terminal tails and associated methyltransferases. FEBS Lett 569(1-3):18-26 {{SGDpaper|S000076596}} PMID 15225602</ref><ref name='S000053738'>Nelson KK and Lemmon SK (1993) Suppressors of clathrin deficiency: overexpression of ubiquitin rescues lethal strains of clathrin-deficient Saccharomyces cerevisiae. Mol Cell Biol 13(1):521-32 {{SGDpaper|S000053738}} PMID 8380227</ref><ref name='S000148260'>Rajyaguru P, et al. (2012) Scd6 Targets eIF4G to Repress Translation: RGG Motif Proteins as a Class of eIF4G-Binding Proteins. Mol Cell 45(2):244-54 |
| − | {{SGDpaper| | + | {{SGDpaper|S000148260}} PMID 22284680</ref> |
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Latest revision as of 13:05, 19 March 2012
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| Systematic name | YPR129W |
| Gene name | SCD6 |
| Aliases | LSM13 |
| Feature type | ORF, Verified |
| Coordinates | Chr XVI:792687..793736 |
| Primary SGDID | S000006333 |
Description of YPR129W: Repressor of translation initiation; binds eIF4G through its RGG domain and inhibits recruitment of the preinitiation complex; also contains an Lsm domain; may have a role in RNA processing; overproduction suppresses null mutation in clathrin heavy chain gene CHC1[1][2][3]
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References
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- ↑ Albrecht M and Lengauer T (2004) Novel Sm-like proteins with long C-terminal tails and associated methyltransferases. FEBS Lett 569(1-3):18-26 SGD PMID 15225602
- ↑ Nelson KK and Lemmon SK (1993) Suppressors of clathrin deficiency: overexpression of ubiquitin rescues lethal strains of clathrin-deficient Saccharomyces cerevisiae. Mol Cell Biol 13(1):521-32 SGD PMID 8380227
- ↑ Rajyaguru P, et al. (2012) Scd6 Targets eIF4G to Repress Translation: RGG Motif Proteins as a Class of eIF4G-Binding Proteins. Mol Cell 45(2):244-54 SGD PMID 22284680
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