Difference between revisions of "YPR141C"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000006345 YPR141C]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000006345 YPR141C]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''KAR3 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''KAR3 ''
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
|nowrap| Chr XVI:817919..815730
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|nowrap| Chr XVI:817923..815734
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000006345
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000006345

Latest revision as of 06:45, 23 January 2012

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Systematic name YPR141C
Gene name KAR3
Aliases OSR11
Feature type ORF, Verified
Coordinates Chr XVI:817923..815734
Primary SGDID S000006345


Description of YPR141C: Minus-end-directed microtubule motor that functions in mitosis and meiosis, localizes to the spindle pole body and localization is dependent on functional Cik1p, required for nuclear fusion during mating; potential Cdc28p substrate[1][2][3][4][5]




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Protein Details

Protein Modification

Modification(s): Phosphorylation

Identified as an efficient substrate of Clb2-Cdk1-as1 in a screen of a proteomic GST-fusion library. [5] [6]





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References

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  1. Mackey AT and Gilbert SP (2003) The ATPase cross-bridge cycle of the Kar3 motor domain. Implications for single head motility. J Biol Chem 278(6):3527-35 SGD PMID 12446697
  2. Meluh PB and Rose MD (1990) KAR3, a kinesin-related gene required for yeast nuclear fusion. Cell 60(6):1029-41 SGD PMID 2138512
  3. Middleton K and Carbon J (1994) KAR3-encoded kinesin is a minus-end-directed motor that functions with centromere binding proteins (CBF3) on an in vitro yeast kinetochore. Proc Natl Acad Sci U S A 91(15):7212-6 SGD PMID 8041770
  4. Page BD, et al. (1994) Localization of the Kar3 kinesin heavy chain-related protein requires the Cik1 interacting protein. J Cell Biol 124(4):507-19 SGD PMID 8106549
  5. 5.0 5.1 Ubersax JA, et al. (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64 SGD PMID 14574415 Cite error: Invalid <ref> tag; name "S000074306" defined multiple times with different content
  6. submitted by Jeff Ubersax on 2004-01-29

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