Difference between revisions of "YPL239W"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000006160 YPL239W]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000006160 YPL239W]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''YAR1 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''YAR1 ''
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'''Description of YPL239W:''' Cytoplasmic ankyrin-repeat containing protein of unknown function, proposed to link the processes of 40S ribosomal subunit biogenesis and adaptation to osmotic and oxidative stress; expression repressed by heat shock<ref name='S000074185'>Huh WK, et al. (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91 {{SGDpaper|S000074185}} PMID 14562095</ref><ref name='S000080092'>Loar JW, et al. (2004) Genetic and biochemical interactions among Yar1, Ltv1 and Rps3 define novel links between environmental stress and ribosome biogenesis in Saccharomyces cerevisiae. Genetics 168(4):1877-89 {{SGDpaper|S000080092}} PMID 15611164</ref><ref name='S000039579'>Lycan DE, et al. (1996) A new Saccharomyces cerevisiae ankyrin repeat-encoding gene required for a normal rate of cell proliferation. Gene 171(1):33-40
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'''Description of YPL239W:''' Nucleocytoplasmic shuttling chaperone specific for Rps3p; binds Rps3p, a small ribosomal rpotein, to prevent subunit aggregation prior to assembly in the 40s ribosome; proposed to link the processes of 40S ribosomal subunit biogenesis and adaptation to osmotic and oxidative stress; expression repressed by heat shock<ref name='S000074185'>Huh WK, et al. (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91 {{SGDpaper|S000074185}} PMID 14562095</ref><ref name='S000150744'>Koch B, et al. (2012) Yar1 protects the ribosomal protein Rps3 from aggregation. J Biol Chem 287(26):21806-15 {{SGDpaper|S000150744}} PMID 22570489</ref><ref name='S000080092'>Loar JW, et al. (2004) Genetic and biochemical interactions among Yar1, Ltv1 and Rps3 define novel links between environmental stress and ribosome biogenesis in Saccharomyces cerevisiae. Genetics 168(4):1877-89 {{SGDpaper|S000080092}} PMID 15611164</ref><ref name='S000039579'>Lycan DE, et al. (1996) A new Saccharomyces cerevisiae ankyrin repeat-encoding gene required for a normal rate of cell proliferation. Gene 171(1):33-40
 
  {{SGDpaper|S000039579}} PMID 8675027</ref>
 
  {{SGDpaper|S000039579}} PMID 8675027</ref>
 
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Latest revision as of 13:05, 10 September 2012

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Systematic name YPL239W
Gene name YAR1
Aliases
Feature type ORF, Verified
Coordinates Chr XVI:99484..100086
Primary SGDID S000006160


Description of YPL239W: Nucleocytoplasmic shuttling chaperone specific for Rps3p; binds Rps3p, a small ribosomal rpotein, to prevent subunit aggregation prior to assembly in the 40s ribosome; proposed to link the processes of 40S ribosomal subunit biogenesis and adaptation to osmotic and oxidative stress; expression repressed by heat shock[1][2][3][4]




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References

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  1. Huh WK, et al. (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91 SGD PMID 14562095
  2. Koch B, et al. (2012) Yar1 protects the ribosomal protein Rps3 from aggregation. J Biol Chem 287(26):21806-15 SGD PMID 22570489
  3. Loar JW, et al. (2004) Genetic and biochemical interactions among Yar1, Ltv1 and Rps3 define novel links between environmental stress and ribosome biogenesis in Saccharomyces cerevisiae. Genetics 168(4):1877-89 SGD PMID 15611164
  4. Lycan DE, et al. (1996) A new Saccharomyces cerevisiae ankyrin repeat-encoding gene required for a normal rate of cell proliferation. Gene 171(1):33-40 SGD PMID 8675027

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