Difference between revisions of "YOR069W"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000005595 YOR069W] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''VPS5 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''VPS5 '' | ||
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
| − | |nowrap| Chr XV: | + | |nowrap| Chr XV:453768..455795 |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000005595 | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000005595 | ||
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| − | '''Description of YOR069W:''' Nexin-1 homolog required for localizing membrane proteins from a prevacuolar/late endosomal compartment back to the late Golgi apparatus; structural component of the retromer membrane coat complex; forms a retromer subcomplex with Vps17p<ref name='S000041460'>Nothwehr SF and Hindes AE (1997) The yeast VPS5/GRD2 gene encodes a sorting nexin-1-like protein required for localizing membrane proteins to the late Golgi. J Cell Sci 110 ( Pt 9)():1063-72 {{SGDpaper|S000041460}} PMID 9175702</ref><ref name='S000074969'>Reddy JV and Seaman MN (2001) Vps26p, a component of retromer, directs the interactions of Vps35p in endosome-to-Golgi retrieval. Mol Biol Cell 12(10):3242-56 {{SGDpaper|S000074969}} PMID 11598206</ref><ref name='S000039451'>Seaman MN, et al. (1998) A membrane coat complex essential for endosome-to-Golgi retrograde transport in yeast. J Cell Biol 142(3):665-81 | + | '''Description of YOR069W:''' Nexin-1 homolog required for localizing membrane proteins from a prevacuolar/late endosomal compartment back to the late Golgi apparatus; structural component of the retromer membrane coat complex; forms a retromer subcomplex with Vps17p; required for recruiting the retromer complex to the endosome membranes<ref name='S000150825'>Liu TT, et al. (2012) Rab GTPase regulation of retromer-mediated cargo export during endosome maturation. Mol Biol Cell 23(13):2505-15 {{SGDpaper|S000150825}} PMID 22593205</ref><ref name='S000041460'>Nothwehr SF and Hindes AE (1997) The yeast VPS5/GRD2 gene encodes a sorting nexin-1-like protein required for localizing membrane proteins to the late Golgi. J Cell Sci 110 ( Pt 9)():1063-72 {{SGDpaper|S000041460}} PMID 9175702</ref><ref name='S000074969'>Reddy JV and Seaman MN (2001) Vps26p, a component of retromer, directs the interactions of Vps35p in endosome-to-Golgi retrieval. Mol Biol Cell 12(10):3242-56 {{SGDpaper|S000074969}} PMID 11598206</ref><ref name='S000039451'>Seaman MN, et al. (1998) A membrane coat complex essential for endosome-to-Golgi retrograde transport in yeast. J Cell Biol 142(3):665-81 |
{{SGDpaper|S000039451}} PMID 9700157</ref> | {{SGDpaper|S000039451}} PMID 9700157</ref> | ||
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Latest revision as of 13:05, 26 September 2012
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| Systematic name | YOR069W |
| Gene name | VPS5 |
| Aliases | GRD2, PEP10, VPT5, YOR29-20 |
| Feature type | ORF, Verified |
| Coordinates | Chr XV:453768..455795 |
| Primary SGDID | S000005595 |
Description of YOR069W: Nexin-1 homolog required for localizing membrane proteins from a prevacuolar/late endosomal compartment back to the late Golgi apparatus; structural component of the retromer membrane coat complex; forms a retromer subcomplex with Vps17p; required for recruiting the retromer complex to the endosome membranes[1][2][3][4]
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References
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- ↑ Liu TT, et al. (2012) Rab GTPase regulation of retromer-mediated cargo export during endosome maturation. Mol Biol Cell 23(13):2505-15 SGD PMID 22593205
- ↑ Nothwehr SF and Hindes AE (1997) The yeast VPS5/GRD2 gene encodes a sorting nexin-1-like protein required for localizing membrane proteins to the late Golgi. J Cell Sci 110 ( Pt 9)():1063-72 SGD PMID 9175702
- ↑ Reddy JV and Seaman MN (2001) Vps26p, a component of retromer, directs the interactions of Vps35p in endosome-to-Golgi retrieval. Mol Biol Cell 12(10):3242-56 SGD PMID 11598206
- ↑ Seaman MN, et al. (1998) A membrane coat complex essential for endosome-to-Golgi retrograde transport in yeast. J Cell Biol 142(3):665-81 SGD PMID 9700157
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