Difference between revisions of "YBR125C"
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{|{{Prettytable}} align = 'right' width = '200px' | {|{{Prettytable}} align = 'right' width = '200px' | ||
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− | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000000329 YBR125C] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''PTC4 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''PTC4 '' | ||
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
− | |nowrap| Chr II: | + | |nowrap| Chr II:488380..487199 |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000000329 | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000000329 | ||
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− | '''Description of YBR125C:''' Cytoplasmic type 2C protein phosphatase; identified as a high-copy number suppressor of | + | '''Description of YBR125C:''' Cytoplasmic type 2C protein phosphatase (PP2C); identified as a high-copy number suppressor of cnb1 mpk1 synthetic lethality; overexpression decreases high-osmolarity induced Hog1p phosphorylation and kinase activity<ref name='S000040841'>Cheng A, et al. (1999) Dephosphorylation of cyclin-dependent kinases by type 2C protein phosphatases. Genes Dev 13(22):2946-57 {{SGDpaper|S000040841}} PMID 10580002</ref><ref name='S000074185'>Huh WK, et al. (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91 {{SGDpaper|S000074185}} PMID 14562095</ref><ref name='S000075013'>Shitamukai A, et al. (2004) Evidence for antagonistic regulation of cell growth by the calcineurin and high osmolarity glycerol pathways in Saccharomyces cerevisiae. J Biol Chem 279(5):3651-61 |
{{SGDpaper|S000075013}} PMID 14583627</ref> | {{SGDpaper|S000075013}} PMID 14583627</ref> | ||
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Latest revision as of 07:45, 23 January 2012
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Systematic name | YBR125C |
Gene name | PTC4 |
Aliases | GCT1 |
Feature type | ORF, Verified |
Coordinates | Chr II:488380..487199 |
Primary SGDID | S000000329 |
Description of YBR125C: Cytoplasmic type 2C protein phosphatase (PP2C); identified as a high-copy number suppressor of cnb1 mpk1 synthetic lethality; overexpression decreases high-osmolarity induced Hog1p phosphorylation and kinase activity[1][2][3]
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References
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- ↑ Cheng A, et al. (1999) Dephosphorylation of cyclin-dependent kinases by type 2C protein phosphatases. Genes Dev 13(22):2946-57 SGD PMID 10580002
- ↑ Huh WK, et al. (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91 SGD PMID 14562095
- ↑ Shitamukai A, et al. (2004) Evidence for antagonistic regulation of cell growth by the calcineurin and high osmolarity glycerol pathways in Saccharomyces cerevisiae. J Biol Chem 279(5):3651-61 SGD PMID 14583627
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