Difference between revisions of "YNR047W"
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− | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000005330 YNR047W] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''FPK1 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''FPK1 '' | ||
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
− | |nowrap| Chr XIV: | + | |nowrap| Chr XIV:708523..711204 |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000005330 | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000005330 | ||
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− | '''Description of YNR047W:''' Ser/Thr protein kinase that regulates the putative phospholipid translocases Lem3p-Dnf1p/Dnf2p; phosphorylates and inhibits upstream inhibitory kinase, Ypk1p; localizes to the cytoplasm, early endosome/TGN compartments, and plasma membrane<ref name='S000061243'>Burchett SA, et al. (2001) Identification of novel pheromone-response regulators through systematic overexpression of 120 protein kinases in yeast. J Biol Chem 276(28):26472-8 {{SGDpaper|S000061243}} PMID 11337509 | + | '''Description of YNR047W:''' Ser/Thr protein kinase that regulates the putative phospholipid translocases Lem3p-Dnf1p/Dnf2p; phosphorylates and inhibits upstream inhibitory kinase, Ypk1p; localizes to the cytoplasm, early endosome/TGN compartments, and plasma membrane<ref name='S000061243'>Burchett SA, et al. (2001) Identification of novel pheromone-response regulators through systematic overexpression of 120 protein kinases in yeast. J Biol Chem 276(28):26472-8 {{SGDpaper|S000061243}} PMID 11337509</ref><ref name='S000128228'>Nakano K, et al. (2008) Protein kinases Fpk1p and Fpk2p are novel regulators of phospholipid asymmetry. Mol Biol Cell 19(4):1783-97 {{SGDpaper|S000128228}} PMID 18199685</ref><ref name='S000132460'>Roelants FM, et al. (2010) A protein kinase network regulates the function of aminophospholipid flippases. Proc Natl Acad Sci U S A 107(1):34-9 {{SGDpaper|S000132460}} PMID 19966303</ref><ref name='S000074306'>Ubersax JA, et al. (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64 |
− | {{SGDpaper| | + | {{SGDpaper|S000074306}} PMID 14574415</ref> |
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Latest revision as of 07:45, 23 January 2012
Share your knowledge...Edit this entry! <protect>
Systematic name | YNR047W |
Gene name | FPK1 |
Aliases | |
Feature type | ORF, Verified |
Coordinates | Chr XIV:708523..711204 |
Primary SGDID | S000005330 |
Description of YNR047W: Ser/Thr protein kinase that regulates the putative phospholipid translocases Lem3p-Dnf1p/Dnf2p; phosphorylates and inhibits upstream inhibitory kinase, Ypk1p; localizes to the cytoplasm, early endosome/TGN compartments, and plasma membrane[1][2][3][4]
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Protein Details
Protein Modification
Modification(s): Phosphorylation
Identified as an efficient substrate of Clb2-Cdk1-as1 in a screen of a proteomic GST-fusion library. [4] [5]
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References
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- ↑ Burchett SA, et al. (2001) Identification of novel pheromone-response regulators through systematic overexpression of 120 protein kinases in yeast. J Biol Chem 276(28):26472-8 SGD PMID 11337509
- ↑ Nakano K, et al. (2008) Protein kinases Fpk1p and Fpk2p are novel regulators of phospholipid asymmetry. Mol Biol Cell 19(4):1783-97 SGD PMID 18199685
- ↑ Roelants FM, et al. (2010) A protein kinase network regulates the function of aminophospholipid flippases. Proc Natl Acad Sci U S A 107(1):34-9 SGD PMID 19966303
- ↑ 4.0 4.1 Ubersax JA, et al. (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64
SGD PMID 14574415 Cite error: Invalid
<ref>
tag; name "S000074306" defined multiple times with different content - ↑ submitted by Jeff Ubersax on 2004-01-29
See Help:Categories on how to add the wiki page for this gene to a Category </protect>