Difference between revisions of "YJR084W"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000003844 YJR084W]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000003844 YJR084W]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''CSN12 ''
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||'' ''
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Aliases'''          ||'' ''
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Aliases'''          ||''CSN12''
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Feature type'''          || ORF, Verified[[Category:ORF]][[Category:ORF, Verified]]
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Feature type'''          || ORF, Verified[[Category:ORF]][[Category:ORF, Verified]]
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
|nowrap| Chr X:583725..584996
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|nowrap| Chr X:583733..585004
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000003844
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000003844
 
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'''Description of YJR084W:''' Subunit of the Cop9 signalosome, which is required for deneddylation, or removal of the ubiquitin-like protein Rub1p from Cdc53p (cullin); involved in mRNA splicing and adaptation to pheromone signaling<ref name='S000071602'>Wee S, et al. (2002) Conservation of the COP9/signalosome in budding yeast. BMC Genet 3():15 {{SGDpaper|S000071602}} PMID 12186635</ref><ref name='S000071980'>Maytal-Kivity V, et al. (2002) COP9 signalosome components play a role in the mating pheromone response of S. cerevisiae. EMBO Rep 3(12):1215-21 {{SGDpaper|S000071980}} PMID 12446563</ref><ref name='S000128899'>Wilmes GM, et al. (2008) A genetic interaction map of RNA-processing factors reveals links between Sem1/Dss1-containing complexes and mRNA export and splicing. Mol Cell 32(5):735-46
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'''Description of YJR084W:''' Protein that forms a complex with Thp3p; may have a role in transcription elongation and/or mRNA splicing; identified as a COP9 signalosome component but phenotype and interactions suggest it may not be involved with the signalosome<ref name='S000143542'>Jimeno S, et al. (2011) New Suppressors of THO Mutations Identify Thp3 (Ypr045c)-Csn12 as a Protein Complex Involved in Transcription Elongation. Mol Cell Biol 31(4):674-685 {{SGDpaper|S000143542}} PMID 21149575</ref><ref name='S000071980'>Maytal-Kivity V, et al. (2002) COP9 signalosome components play a role in the mating pheromone response of S. cerevisiae. EMBO Rep 3(12):1215-21 {{SGDpaper|S000071980}} PMID 12446563</ref><ref name='S000071602'>Wee S, et al. (2002) Conservation of the COP9/signalosome in budding yeast. BMC Genet 3():15 {{SGDpaper|S000071602}} PMID 12186635</ref><ref name='S000128899'>Wilmes GM, et al. (2008) A genetic interaction map of RNA-processing factors reveals links between Sem1/Dss1-containing complexes and mRNA export and splicing. Mol Cell 32(5):735-46
 
  {{SGDpaper|S000128899}} PMID 19061648</ref>
 
  {{SGDpaper|S000128899}} PMID 19061648</ref>
 
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Latest revision as of 06:45, 23 January 2012

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Systematic name YJR084W
Gene name
Aliases CSN12
Feature type ORF, Verified
Coordinates Chr X:583733..585004
Primary SGDID S000003844


Description of YJR084W: Protein that forms a complex with Thp3p; may have a role in transcription elongation and/or mRNA splicing; identified as a COP9 signalosome component but phenotype and interactions suggest it may not be involved with the signalosome[1][2][3][4]




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References

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  1. Jimeno S, et al. (2011) New Suppressors of THO Mutations Identify Thp3 (Ypr045c)-Csn12 as a Protein Complex Involved in Transcription Elongation. Mol Cell Biol 31(4):674-685 SGD PMID 21149575
  2. Maytal-Kivity V, et al. (2002) COP9 signalosome components play a role in the mating pheromone response of S. cerevisiae. EMBO Rep 3(12):1215-21 SGD PMID 12446563
  3. Wee S, et al. (2002) Conservation of the COP9/signalosome in budding yeast. BMC Genet 3():15 SGD PMID 12186635
  4. Wilmes GM, et al. (2008) A genetic interaction map of RNA-processing factors reveals links between Sem1/Dss1-containing complexes and mRNA export and splicing. Mol Cell 32(5):735-46 SGD PMID 19061648

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