Difference between revisions of "YLR117C"
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− | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000004107 YLR117C] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''CLF1 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''CLF1 '' | ||
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
− | |nowrap| Chr XII: | + | |nowrap| Chr XII:384534..382471 |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000004107 | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000004107 | ||
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− | '''Description of YLR117C:''' Member of the NineTeen Complex (NTC) that contains Prp19p and stabilizes U6 snRNA in catalytic forms of the spliceosome containing U2, U5, and U6 snRNAs; homolog of Drosophila crooked neck protein; interacts with U1 snRNP proteins | + | '''Description of YLR117C:''' Member of the NineTeen Complex (NTC) that contains Prp19p and stabilizes U6 snRNA in catalytic forms of the spliceosome containing U2, U5, and U6 snRNAs; homolog of Drosophila crooked neck protein; interacts with U1 snRNP proteins<ref name='S000059451'>Ben-Yehuda S, et al. (2000) Genetic and physical interactions between factors involved in both cell cycle progression and pre-mRNA splicing in Saccharomyces cerevisiae. Genetics 156(4):1503-17 {{SGDpaper|S000059451}} PMID 11102353</ref><ref name='S000115006'>Chen CH, et al. (2006) Functional links between the Prp19-associated complex, U4/U6 biogenesis, and spliceosome recycling. RNA 12(5):765-74 {{SGDpaper|S000115006}} PMID 16540691</ref><ref name='S000052652'>Chung S, et al. (1999) Yeast ortholog of the Drosophila crooked neck protein promotes spliceosome assembly through stable U4/U6.U5 snRNP addition. RNA 5(8):1042-54 {{SGDpaper|S000052652}} PMID 10445879</ref><ref name='S000115084'>Tardiff DF and Rosbash M (2006) Arrested yeast splicing complexes indicate stepwise snRNP recruitment during in vivo spliceosome assembly. RNA 12(6):968-79 {{SGDpaper|S000115084}} PMID 16618970</ref><ref name='S000080962'>Vincent K, et al. (2003) Genetic interactions with CLF1 identify additional pre-mRNA splicing factors and a link between activators of yeast vesicular transport and splicing. Genetics 164(3):895-907 {{SGDpaper|S000080962}} PMID 12871902</ref><ref name='S000081629'>Wang Q, et al. (2003) The Clf1p splicing factor promotes spliceosome assembly through N-terminal tetratricopeptide repeat contacts. J Biol Chem 278(10):7875-83 |
− | {{SGDpaper| | + | {{SGDpaper|S000081629}} PMID 12509417</ref> |
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Latest revision as of 07:45, 23 January 2012
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Systematic name | YLR117C |
Gene name | CLF1 |
Aliases | NTC77, SYF3 |
Feature type | ORF, Verified |
Coordinates | Chr XII:384534..382471 |
Primary SGDID | S000004107 |
Description of YLR117C: Member of the NineTeen Complex (NTC) that contains Prp19p and stabilizes U6 snRNA in catalytic forms of the spliceosome containing U2, U5, and U6 snRNAs; homolog of Drosophila crooked neck protein; interacts with U1 snRNP proteins[1][2][3][4][5][6]
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References
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- ↑ Ben-Yehuda S, et al. (2000) Genetic and physical interactions between factors involved in both cell cycle progression and pre-mRNA splicing in Saccharomyces cerevisiae. Genetics 156(4):1503-17 SGD PMID 11102353
- ↑ Chen CH, et al. (2006) Functional links between the Prp19-associated complex, U4/U6 biogenesis, and spliceosome recycling. RNA 12(5):765-74 SGD PMID 16540691
- ↑ Chung S, et al. (1999) Yeast ortholog of the Drosophila crooked neck protein promotes spliceosome assembly through stable U4/U6.U5 snRNP addition. RNA 5(8):1042-54 SGD PMID 10445879
- ↑ Tardiff DF and Rosbash M (2006) Arrested yeast splicing complexes indicate stepwise snRNP recruitment during in vivo spliceosome assembly. RNA 12(6):968-79 SGD PMID 16618970
- ↑ Vincent K, et al. (2003) Genetic interactions with CLF1 identify additional pre-mRNA splicing factors and a link between activators of yeast vesicular transport and splicing. Genetics 164(3):895-907 SGD PMID 12871902
- ↑ Wang Q, et al. (2003) The Clf1p splicing factor promotes spliceosome assembly through N-terminal tetratricopeptide repeat contacts. J Biol Chem 278(10):7875-83 SGD PMID 12509417
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