Difference between revisions of "YPL233W"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?locus=YPL233W YPL233W]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000006154 YPL233W]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''NSL1 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''NSL1 ''
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|nowrap| Chr XVI:106172..106822
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000006154
 
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'''Description of {{PAGENAME}}:''' Essential component of the MIND kinetochore complex (Mtw1p Including Nnf1p-Nsl1p-Dsn1p) which joins kinetochore subunits contacting DNA to those contacting microtubules; required for accurate chromosome segregation<ref name='S000071701'>Euskirchen GM (2002) Nnf1p, Dsn1p, Mtw1p, and Nsl1p: a new group of proteins important for chromosome segregation in Saccharomyces cerevisiae. Eukaryot Cell 1(2):229-40
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'''Description of YPL233W:''' Essential component of the MIND kinetochore complex (Mtw1p Including Nnf1p-Nsl1p-Dsn1p) which joins kinetochore subunits contacting DNA to those contacting microtubules; required for accurate chromosome segregation<ref name='S000071701'>Euskirchen GM (2002) Nnf1p, Dsn1p, Mtw1p, and Nsl1p: a new group of proteins important for chromosome segregation in Saccharomyces cerevisiae. Eukaryot Cell 1(2):229-40
 
  {{SGDpaper|S000071701}} PMID 12455957</ref>
 
  {{SGDpaper|S000071701}} PMID 12455957</ref>
 
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=== Interactions ===
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==== Physical ====
 
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Physical interaction with DSN1 [[Category:Physical Interactions with DSN1]]<br>
 
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Nsl1p co-immunoprecipitates Dsn1p. <ref name='S000075182'>Pinsky BA, et al. (2003) An Mtw1 complex promotes kinetochore biorientation that is monitored by the Ipl1/Aurora protein kinase. Dev Cell 5(5):735-45 {{SGDpaper|S000075182}} PMID 14602074</ref> <ref name = 'CAset9883-2004-03-04'>submitted by [http://db.yeastgenome.org/cgi-bin/colleague/colleagueSearch?id=9883 Benjamin Pinsky] on 2004-03-04</ref>
 
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Physical interaction with CSE4 [[Category:Physical Interactions with CSE4]]<br>
 
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Cse4p immunoprecipitates with Nsl1p. <ref name='S000075182'>Pinsky BA, et al. (2003) An Mtw1 complex promotes kinetochore biorientation that is monitored by the Ipl1/Aurora protein kinase. Dev Cell 5(5):735-45 {{SGDpaper|S000075182}} PMID 14602074</ref> <ref name = 'CAset9883-2004-03-04'>submitted by [http://db.yeastgenome.org/cgi-bin/colleague/colleagueSearch?id=9883 Benjamin Pinsky] on 2004-03-04</ref>
 
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==Community Commentary==
 
==Community Commentary==
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Specifically higher expression in carbon limited chemostat cultures versus carbon excess.
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<ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur.
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J Biol Chem 278(5):3265-74</ref>
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==References==
 
==References==
 
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Latest revision as of 06:45, 23 January 2012

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Systematic name YPL233W
Gene name NSL1
Aliases
Feature type ORF, Verified
Coordinates Chr XVI:106172..106822
Primary SGDID S000006154


Description of YPL233W: Essential component of the MIND kinetochore complex (Mtw1p Including Nnf1p-Nsl1p-Dsn1p) which joins kinetochore subunits contacting DNA to those contacting microtubules; required for accurate chromosome segregation[1]




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Community Commentary

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Interactions

Physical

Physical interaction with DSN1
Nsl1p co-immunoprecipitates Dsn1p. [2] [3]

Physical interaction with CSE4
Cse4p immunoprecipitates with Nsl1p. [2] [3]




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References

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  1. ↑ Euskirchen GM (2002) Nnf1p, Dsn1p, Mtw1p, and Nsl1p: a new group of proteins important for chromosome segregation in Saccharomyces cerevisiae. Eukaryot Cell 1(2):229-40 SGD PMID 12455957
  2. ↑ 2.0 2.1 Pinsky BA, et al. (2003) An Mtw1 complex promotes kinetochore biorientation that is monitored by the Ipl1/Aurora protein kinase. Dev Cell 5(5):735-45 SGD PMID 14602074
  3. ↑ 3.0 3.1 submitted by Benjamin Pinsky on 2004-03-04

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