Difference between revisions of "YML036W"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000004500 YML036W] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''CGI121 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''CGI121 '' | ||
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| − | '''Description of YML036W:''' | + | '''Description of YML036W:''' Component of the EKC/KEOPS complex with Bud32p, Kae1p, Pcc1p, and Gon7p; EKC/KEOPS complex is required for t6A tRNA modification and may have roles in telomere maintenance and transcription; Cgi121p is dispensable for tRNA modification<ref name='S000114691'>Downey M, et al. (2006) A genome-wide screen identifies the evolutionarily conserved KEOPS complex as a telomere regulator. Cell 124(6):1155-68 {{SGDpaper|S000114691}} PMID 16564010</ref><ref name='S000117374'>Kisseleva-Romanova E, et al. (2006) Yeast homolog of a cancer-testis antigen defines a new transcription complex. EMBO J 25(15):3576-85 {{SGDpaper|S000117374}} PMID 16874308</ref><ref name='S000142370'>Srinivasan M, et al. (2011) The highly conserved KEOPS/EKC complex is essential for a universal tRNA modification, t6A. EMBO J 30(5):873-81 |
| − | {{SGDpaper| | + | {{SGDpaper|S000142370}} PMID 21183954</ref> |
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Latest revision as of 06:45, 23 January 2012
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| Systematic name | YML036W |
| Gene name | CGI121 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr XIII:205642..206293 |
| Primary SGDID | S000004500 |
Description of YML036W: Component of the EKC/KEOPS complex with Bud32p, Kae1p, Pcc1p, and Gon7p; EKC/KEOPS complex is required for t6A tRNA modification and may have roles in telomere maintenance and transcription; Cgi121p is dispensable for tRNA modification[1][2][3]
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References
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- ↑ Downey M, et al. (2006) A genome-wide screen identifies the evolutionarily conserved KEOPS complex as a telomere regulator. Cell 124(6):1155-68 SGD PMID 16564010
- ↑ Kisseleva-Romanova E, et al. (2006) Yeast homolog of a cancer-testis antigen defines a new transcription complex. EMBO J 25(15):3576-85 SGD PMID 16874308
- ↑ Srinivasan M, et al. (2011) The highly conserved KEOPS/EKC complex is essential for a universal tRNA modification, t6A. EMBO J 30(5):873-81 SGD PMID 21183954
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