Difference between revisions of "YGR222W"
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− | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000003454 YGR222W] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''PET54 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''PET54 '' | ||
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
− | |nowrap| Chr VII: | + | |nowrap| Chr VII:939923..940804 |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000003454 | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000003454 | ||
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− | '''Description of YGR222W:''' Mitochondrial inner membrane protein | + | '''Description of YGR222W:''' Mitochondrial inner membrane protein; binds to the 5' UTR of the COX3 mRNA to activate its translation together with Pet122p and Pet494p; also binds to the COX1 Group I intron AI5 beta to facilitate exon ligation during splicing<ref name='S000054211'>Costanzo MC, et al. (1989) The PET54 gene of Saccharomyces cerevisiae: characterization of a nuclear gene encoding a mitochondrial translational activator and subcellular localization of its product. Genetics 122(2):297-305 {{SGDpaper|S000054211}} PMID 2548921</ref><ref name='S000125994'>Kaspar BJ, et al. (2008) A shared RNA-binding site in the Pet54 protein is required for translational activation and group I intron splicing in yeast mitochondria. Nucleic Acids Res 36(9):2958-68 {{SGDpaper|S000125994}} PMID 18388132</ref><ref name='S000072504'>Naithani S, et al. (2003) Interactions among COX1, COX2, and COX3 mRNA-specific translational activator proteins on the inner surface of the mitochondrial inner membrane of Saccharomyces cerevisiae. Mol Biol Cell 14(1):324-33 {{SGDpaper|S000072504}} PMID 12529447</ref><ref name='S000047957'>Valencik ML, et al. (1989) Disruption of the yeast nuclear PET54 gene blocks excision of mitochondrial intron aI5 beta from pre-mRNA for cytochrome c oxidase subunit I. EMBO J 8(12):3899-904 |
− | {{SGDpaper| | + | {{SGDpaper|S000047957}} PMID 2555177</ref> |
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Latest revision as of 07:45, 23 January 2012
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Systematic name | YGR222W |
Gene name | PET54 |
Aliases | |
Feature type | ORF, Verified |
Coordinates | Chr VII:939923..940804 |
Primary SGDID | S000003454 |
Description of YGR222W: Mitochondrial inner membrane protein; binds to the 5' UTR of the COX3 mRNA to activate its translation together with Pet122p and Pet494p; also binds to the COX1 Group I intron AI5 beta to facilitate exon ligation during splicing[1][2][3][4]
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References
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- ↑ Costanzo MC, et al. (1989) The PET54 gene of Saccharomyces cerevisiae: characterization of a nuclear gene encoding a mitochondrial translational activator and subcellular localization of its product. Genetics 122(2):297-305 SGD PMID 2548921
- ↑ Kaspar BJ, et al. (2008) A shared RNA-binding site in the Pet54 protein is required for translational activation and group I intron splicing in yeast mitochondria. Nucleic Acids Res 36(9):2958-68 SGD PMID 18388132
- ↑ Naithani S, et al. (2003) Interactions among COX1, COX2, and COX3 mRNA-specific translational activator proteins on the inner surface of the mitochondrial inner membrane of Saccharomyces cerevisiae. Mol Biol Cell 14(1):324-33 SGD PMID 12529447
- ↑ Valencik ML, et al. (1989) Disruption of the yeast nuclear PET54 gene blocks excision of mitochondrial intron aI5 beta from pre-mRNA for cytochrome c oxidase subunit I. EMBO J 8(12):3899-904 SGD PMID 2555177
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