Difference between revisions of "YDR139C"
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− | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000002546 YDR139C] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''RUB1 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''RUB1 '' | ||
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
− | |nowrap| Chr IV: | + | |nowrap| Chr IV:733924..733618 |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000002546 | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000002546 | ||
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− | '''Description of YDR139C:''' Ubiquitin-like protein with similarity to mammalian NEDD8; conjugation (neddylation) substrates include the cullins Cdc53p, Rtt101p, and Cul3p; activated by Ula1p and Uba3p (E1 enzyme pair); conjugation mediated by Ubc12p (E2 enzyme)<ref name='S000042395'>Lammer D, et al. (1998) Modification of yeast Cdc53p by the ubiquitin-related protein rub1p affects function of the SCFCdc4 complex. Genes Dev 12(7):914-26 {{SGDpaper|S000042395}} PMID 9531531</ref><ref name=' | + | '''Description of YDR139C:''' Ubiquitin-like protein with similarity to mammalian NEDD8; conjugation (neddylation) substrates include the cullins Cdc53p, Rtt101p, and Cul3p; activated by Ula1p and Uba3p (E1 enzyme pair); conjugation mediated by Ubc12p (E2 enzyme)<ref name='S000061637'>Hochstrasser M (2000) Biochemistry. All in the ubiquitin family. Science 289(5479):563-4 {{SGDpaper|S000061637}} PMID 10939967</ref><ref name='S000042395'>Lammer D, et al. (1998) Modification of yeast Cdc53p by the ubiquitin-related protein rub1p affects function of the SCFCdc4 complex. Genes Dev 12(7):914-26 {{SGDpaper|S000042395}} PMID 9531531</ref><ref name='S000075344'>Laplaza JM, et al. (2004) Saccharomyces cerevisiae ubiquitin-like protein Rub1 conjugates to cullin proteins Rtt101 and Cul3 in vivo. Biochem J 377(Pt 2):459-67 {{SGDpaper|S000075344}} PMID 14519104</ref><ref name='S000050724'>Liakopoulos D, et al. (1998) A novel protein modification pathway related to the ubiquitin system. EMBO J 17(8):2208-14 |
− | {{SGDpaper| | + | {{SGDpaper|S000050724}} PMID 9545234</ref> |
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Latest revision as of 07:45, 23 January 2012
Share your knowledge...Edit this entry! <protect>
Systematic name | YDR139C |
Gene name | RUB1 |
Aliases | |
Feature type | ORF, Verified |
Coordinates | Chr IV:733924..733618 |
Primary SGDID | S000002546 |
Description of YDR139C: Ubiquitin-like protein with similarity to mammalian NEDD8; conjugation (neddylation) substrates include the cullins Cdc53p, Rtt101p, and Cul3p; activated by Ula1p and Uba3p (E1 enzyme pair); conjugation mediated by Ubc12p (E2 enzyme)[1][2][3][4]
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References
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- ↑ Hochstrasser M (2000) Biochemistry. All in the ubiquitin family. Science 289(5479):563-4 SGD PMID 10939967
- ↑ Lammer D, et al. (1998) Modification of yeast Cdc53p by the ubiquitin-related protein rub1p affects function of the SCFCdc4 complex. Genes Dev 12(7):914-26 SGD PMID 9531531
- ↑ Laplaza JM, et al. (2004) Saccharomyces cerevisiae ubiquitin-like protein Rub1 conjugates to cullin proteins Rtt101 and Cul3 in vivo. Biochem J 377(Pt 2):459-67 SGD PMID 14519104
- ↑ Liakopoulos D, et al. (1998) A novel protein modification pathway related to the ubiquitin system. EMBO J 17(8):2208-14 SGD PMID 9545234
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