Difference between revisions of "YDR113C"
SGDwikiBot (talk | contribs) (Automated import of articles) |
SGDwikiBot (talk | contribs) (Automated import of articles) |
||
(4 intermediate revisions by the same user not shown) | |||
Line 4: | Line 4: | ||
{|{{Prettytable}} align = 'right' width = '200px' | {|{{Prettytable}} align = 'right' width = '200px' | ||
|- | |- | ||
− | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000002520 YDR113C] |
|- | |- | ||
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''PDS1 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''PDS1 '' | ||
Line 13: | Line 13: | ||
|- | |- | ||
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
− | |nowrap| Chr IV: | + | |nowrap| Chr IV:681617..680496 |
|- | |- | ||
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000002520 | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000002520 | ||
|} | |} | ||
<br> | <br> | ||
− | '''Description of YDR113C:''' Securin | + | '''Description of YDR113C:''' Securin, inhibits anaphase by binding separin Esp1p; blocks cyclin destruction and mitotic exit, essential for meiotic progression and mitotic cell cycle arrest; localization is cell-cycle dependent and regulated by Cdc28p phosphorylation<ref name='S000054076'>Ciosk R, et al. (1998) An ESP1/PDS1 complex regulates loss of sister chromatid cohesion at the metaphase to anaphase transition in yeast. Cell 93(6):1067-76 {{SGDpaper|S000054076}} PMID 9635435</ref><ref name='S000051557'>Cohen-Fix O and Koshland D (1997) The anaphase inhibitor of Saccharomyces cerevisiae Pds1p is a target of the DNA damage checkpoint pathway. Proc Natl Acad Sci U S A 94(26):14361-6 {{SGDpaper|S000051557}} PMID 9405617</ref><ref name='S000042563'>Cohen-Fix O, et al. (1996) Anaphase initiation in Saccharomyces cerevisiae is controlled by the APC-dependent degradation of the anaphase inhibitor Pds1p. Genes Dev 10(24):3081-93 {{SGDpaper|S000042563}} PMID 8985178</ref><ref name='S000128287'>Cooper KF, et al. (2009) Pds1p Is Required for Meiotic Recombination and Prophase I Progression in Saccharomyces cerevisiae. Genetics 181(1):65-79 |
− | {{SGDpaper| | + | {{SGDpaper|S000128287}} PMID 19001291</ref> |
<br> | <br> | ||
<br> | <br> |
Latest revision as of 07:45, 23 January 2012
Share your knowledge...Edit this entry! <protect>
Systematic name | YDR113C |
Gene name | PDS1 |
Aliases | |
Feature type | ORF, Verified |
Coordinates | Chr IV:681617..680496 |
Primary SGDID | S000002520 |
Description of YDR113C: Securin, inhibits anaphase by binding separin Esp1p; blocks cyclin destruction and mitotic exit, essential for meiotic progression and mitotic cell cycle arrest; localization is cell-cycle dependent and regulated by Cdc28p phosphorylation[1][2][3][4]
</protect>
Community Commentary
About Community Commentary. Please share your knowledge!
Protein Details
Protein Modification
Modification(s): Phosphorylation
Identified as an efficient substrate of Clb2-Cdk1-as1 in a screen of a proteomic GST-fusion library. [5] [6]
<protect>
References
See Help:References on how to add references
- ↑ Ciosk R, et al. (1998) An ESP1/PDS1 complex regulates loss of sister chromatid cohesion at the metaphase to anaphase transition in yeast. Cell 93(6):1067-76 SGD PMID 9635435
- ↑ Cohen-Fix O and Koshland D (1997) The anaphase inhibitor of Saccharomyces cerevisiae Pds1p is a target of the DNA damage checkpoint pathway. Proc Natl Acad Sci U S A 94(26):14361-6 SGD PMID 9405617
- ↑ Cohen-Fix O, et al. (1996) Anaphase initiation in Saccharomyces cerevisiae is controlled by the APC-dependent degradation of the anaphase inhibitor Pds1p. Genes Dev 10(24):3081-93 SGD PMID 8985178
- ↑ Cooper KF, et al. (2009) Pds1p Is Required for Meiotic Recombination and Prophase I Progression in Saccharomyces cerevisiae. Genetics 181(1):65-79 SGD PMID 19001291
- ↑ Ubersax JA, et al. (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64 SGD PMID 14574415
- ↑ submitted by Jeff Ubersax on 2004-01-21
See Help:Categories on how to add the wiki page for this gene to a Category </protect>