Difference between revisions of "YHR087W"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000001129 YHR087W]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000001129 YHR087W]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''RTC3 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''RTC3 ''
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Aliases'''          ||'' ''
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Aliases'''          ||''HGI1''
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Feature type'''          || ORF, Verified[[Category:ORF]][[Category:ORF, Verified]]
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Feature type'''          || ORF, Verified[[Category:ORF]][[Category:ORF, Verified]]
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
|nowrap| Chr VIII:280822..281157
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|nowrap| Chr VIII:280820..281155
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000001129
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000001129
 
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'''Description of YHR087W:''' Protein of unknown function involved in RNA metabolism; has structural similarity to SBDS, the human protein mutated in Shwachman-Diamond Syndrome (the yeast SBDS ortholog = SDO1); null mutation suppresses cdc13-1 temperature sensitivity<ref name='S000115063'>Boocock GR, et al. (2006) Phylogeny, sequence conservation, and functional complementation of the SBDS protein family. Genomics 87(6):758-71 {{SGDpaper|S000115063}} PMID 16529906</ref><ref name='S000080728'>Shammas C, et al. (2005) Structural and mutational analysis of the SBDS protein family. Insight into the leukemia-associated Shwachman-Diamond Syndrome. J Biol Chem 280(19):19221-9 {{SGDpaper|S000080728}} PMID 15701631</ref><ref name='S000080732'>Savchenko A, et al. (2005) The Shwachman-Bodian-Diamond syndrome protein family is involved in RNA metabolism. J Biol Chem 280(19):19213-20 {{SGDpaper|S000080732}} PMID 15701634</ref><ref name='S000127972'>Addinall SG, et al. (2008) A Genomewide Suppressor and Enhancer Analysis of cdc13-1 Reveals Varied Cellular Processes Influencing Telomere Capping in Saccharomyces cerevisiae. Genetics 180(4):2251-66
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'''Description of YHR087W:''' Protein of unknown function involved in RNA metabolism; has structural similarity to SBDS, the human protein mutated in Shwachman-Diamond Syndrome (the yeast SBDS ortholog = SDO1); null mutation suppresses cdc13-1 temperature sensitivity<ref name='S000127972'>Addinall SG, et al. (2008) A Genomewide Suppressor and Enhancer Analysis of cdc13-1 Reveals Varied Cellular Processes Influencing Telomere Capping in Saccharomyces cerevisiae. Genetics 180(4):2251-66 {{SGDpaper|S000127972}} PMID 18845848</ref><ref name='S000115063'>Boocock GR, et al. (2006) Phylogeny, sequence conservation, and functional complementation of the SBDS protein family. Genomics 87(6):758-71 {{SGDpaper|S000115063}} PMID 16529906</ref><ref name='S000080732'>Savchenko A, et al. (2005) The Shwachman-Bodian-Diamond syndrome protein family is involved in RNA metabolism. J Biol Chem 280(19):19213-20 {{SGDpaper|S000080732}} PMID 15701634</ref><ref name='S000080728'>Shammas C, et al. (2005) Structural and mutational analysis of the SBDS protein family. Insight into the leukemia-associated Shwachman-Diamond Syndrome. J Biol Chem 280(19):19221-9
  {{SGDpaper|S000127972}} PMID 18845848</ref>
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  {{SGDpaper|S000080728}} PMID 15701631</ref>
 
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Latest revision as of 13:05, 13 July 2012

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Systematic name YHR087W
Gene name RTC3
Aliases HGI1
Feature type ORF, Verified
Coordinates Chr VIII:280820..281155
Primary SGDID S000001129


Description of YHR087W: Protein of unknown function involved in RNA metabolism; has structural similarity to SBDS, the human protein mutated in Shwachman-Diamond Syndrome (the yeast SBDS ortholog = SDO1); null mutation suppresses cdc13-1 temperature sensitivity[1][2][3][4]




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References

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  1. Addinall SG, et al. (2008) A Genomewide Suppressor and Enhancer Analysis of cdc13-1 Reveals Varied Cellular Processes Influencing Telomere Capping in Saccharomyces cerevisiae. Genetics 180(4):2251-66 SGD PMID 18845848
  2. Boocock GR, et al. (2006) Phylogeny, sequence conservation, and functional complementation of the SBDS protein family. Genomics 87(6):758-71 SGD PMID 16529906
  3. Savchenko A, et al. (2005) The Shwachman-Bodian-Diamond syndrome protein family is involved in RNA metabolism. J Biol Chem 280(19):19213-20 SGD PMID 15701634
  4. Shammas C, et al. (2005) Structural and mutational analysis of the SBDS protein family. Insight into the leukemia-associated Shwachman-Diamond Syndrome. J Biol Chem 280(19):19221-9 SGD PMID 15701631

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