Difference between revisions of "YCL024W"
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− | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000000529 YCL024W] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''KCC4 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''KCC4 '' | ||
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− | '''Description of YCL024W:''' Protein kinase of the bud neck involved in the septin checkpoint | + | '''Description of YCL024W:''' Protein kinase of the bud neck involved in the septin checkpoint; associates with septin proteins, negatively regulates Swe1p by phosphorylation, shows structural homology to bud neck kinases Gin4p and Hsl1p; KCC4 has a paralog, GIN4, that arose from the whole genome duplication<ref name='S000051063'>Barral Y, et al. (1999) Nim1-related kinases coordinate cell cycle progression with the organization of the peripheral cytoskeleton in yeast. Genes Dev 13(2):176-87 {{SGDpaper|S000051063}} PMID 9925642</ref><ref name='S000113653'>Byrne KP and Wolfe KH (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61 {{SGDpaper|S000113653}} PMID 16169922</ref><ref name='S000059506'>Okuzaki D and Nojima H (2001) Kcc4 associates with septin proteins of Saccharomyces cerevisiae. FEBS Lett 489(2-3):197-201 {{SGDpaper|S000059506}} PMID 11165249</ref><ref name='S000073214'>Okuzaki D, et al. (2003) The Saccharomyces cerevisiae bud-neck proteins Kcc4 and Gin4 have distinct but partially-overlapping cellular functions. Genes Genet Syst 78(2):113-26 |
{{SGDpaper|S000073214}} PMID 12773812</ref> | {{SGDpaper|S000073214}} PMID 12773812</ref> | ||
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Latest revision as of 14:05, 16 August 2012
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Systematic name | YCL024W |
Gene name | KCC4 |
Aliases | |
Feature type | ORF, Verified |
Coordinates | Chr III:79162..82275 |
Primary SGDID | S000000529 |
Description of YCL024W: Protein kinase of the bud neck involved in the septin checkpoint; associates with septin proteins, negatively regulates Swe1p by phosphorylation, shows structural homology to bud neck kinases Gin4p and Hsl1p; KCC4 has a paralog, GIN4, that arose from the whole genome duplication[1][2][3][4]
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References
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- ↑ Barral Y, et al. (1999) Nim1-related kinases coordinate cell cycle progression with the organization of the peripheral cytoskeleton in yeast. Genes Dev 13(2):176-87 SGD PMID 9925642
- ↑ Byrne KP and Wolfe KH (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61 SGD PMID 16169922
- ↑ Okuzaki D and Nojima H (2001) Kcc4 associates with septin proteins of Saccharomyces cerevisiae. FEBS Lett 489(2-3):197-201 SGD PMID 11165249
- ↑ Okuzaki D, et al. (2003) The Saccharomyces cerevisiae bud-neck proteins Kcc4 and Gin4 have distinct but partially-overlapping cellular functions. Genes Genet Syst 78(2):113-26 SGD PMID 12773812
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