Difference between revisions of "YER048W-A"
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− | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000007237 YER048W-A] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''ISD11 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''ISD11 '' | ||
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
− | |nowrap| Chr V: | + | |nowrap| Chr V:250718..251002 |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000007237 | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000007237 | ||
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− | '''Description of YER048W-A:''' | + | '''Description of YER048W-A:''' Cysteine desulfurase (Nfs1p) activator; essential for the formation of the persulfide intermediate at the desulfurase active site during pyridoxal phosphate-dependent desulfuration of cysteine; required for mitochondrial iron-sulfur cluster biosynthesis<ref name='S000113860'>Adam AC, et al. (2006) The Nfs1 interacting protein Isd11 has an essential role in Fe/S cluster biogenesis in mitochondria. EMBO J 25(1):174-83 {{SGDpaper|S000113860}} PMID 16341090</ref><ref name='S000146765'>Pandey A, et al. (2011) Isd11p activates the mitochondrial cysteine desulfurase, Nfs1p. J Biol Chem () {{SGDpaper|S000146765}} PMID 21908622</ref><ref name='S000120450'>Wiedemann N, et al. (2006) Essential role of Isd11 in mitochondrial iron-sulfur cluster synthesis on Isu scaffold proteins. EMBO J 25(1):184-95 |
− | {{SGDpaper| | + | {{SGDpaper|S000120450}} PMID 16341089</ref> |
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Latest revision as of 07:45, 23 January 2012
Share your knowledge...Edit this entry! <protect>
Systematic name | YER048W-A |
Gene name | ISD11 |
Aliases | |
Feature type | ORF, Verified |
Coordinates | Chr V:250718..251002 |
Primary SGDID | S000007237 |
Description of YER048W-A: Cysteine desulfurase (Nfs1p) activator; essential for the formation of the persulfide intermediate at the desulfurase active site during pyridoxal phosphate-dependent desulfuration of cysteine; required for mitochondrial iron-sulfur cluster biosynthesis[1][2][3]
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References
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- ↑ Adam AC, et al. (2006) The Nfs1 interacting protein Isd11 has an essential role in Fe/S cluster biogenesis in mitochondria. EMBO J 25(1):174-83 SGD PMID 16341090
- ↑ Pandey A, et al. (2011) Isd11p activates the mitochondrial cysteine desulfurase, Nfs1p. J Biol Chem () SGD PMID 21908622
- ↑ Wiedemann N, et al. (2006) Essential role of Isd11 in mitochondrial iron-sulfur cluster synthesis on Isu scaffold proteins. EMBO J 25(1):184-95 SGD PMID 16341089
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