Difference between revisions of "YOR057W"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000005583 YOR057W] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''SGT1 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''SGT1 '' | ||
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
| − | |nowrap| Chr XV: | + | |nowrap| Chr XV:432186..433373 |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000005583 | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000005583 | ||
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<br> | <br> | ||
| − | '''Description of YOR057W:''' | + | '''Description of YOR057W:''' Cochaperone protein; regulates activity of adenylyl cyclase Cyr1p; involved in kinetochore complex assembly; associates with the SCF (Skp1p/Cdc53p/F box protein) ubiquitin ligase complex; acts as a linker between Skp1p and HSP90 complexes<ref name='S000118278'>Catlett MG and Kaplan KB (2006) Sgt1p is a unique co-chaperone that acts as a client adaptor to link Hsp90 to Skp1p. J Biol Chem 281(44):33739-48 {{SGDpaper|S000118278}} PMID 16945921</ref><ref name='S000071668'>Dubacq C, et al. (2002) Sgt1p contributes to cyclic AMP pathway activity and physically interacts with the adenylyl cyclase Cyr1p/Cdc35p in budding yeast. Eukaryot Cell 1(4):568-82 {{SGDpaper|S000071668}} PMID 12456005</ref><ref name='S000047894'>Kitagawa K, et al. (1999) SGT1 encodes an essential component of the yeast kinetochore assembly pathway and a novel subunit of the SCF ubiquitin ligase complex. Mol Cell 4(1):21-33 |
{{SGDpaper|S000047894}} PMID 10445024</ref> | {{SGDpaper|S000047894}} PMID 10445024</ref> | ||
<br> | <br> | ||
Latest revision as of 06:45, 23 January 2012
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| Systematic name | YOR057W |
| Gene name | SGT1 |
| Aliases | YOR29-08 |
| Feature type | ORF, Verified |
| Coordinates | Chr XV:432186..433373 |
| Primary SGDID | S000005583 |
Description of YOR057W: Cochaperone protein; regulates activity of adenylyl cyclase Cyr1p; involved in kinetochore complex assembly; associates with the SCF (Skp1p/Cdc53p/F box protein) ubiquitin ligase complex; acts as a linker between Skp1p and HSP90 complexes[1][2][3]
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References
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- ↑ Catlett MG and Kaplan KB (2006) Sgt1p is a unique co-chaperone that acts as a client adaptor to link Hsp90 to Skp1p. J Biol Chem 281(44):33739-48 SGD PMID 16945921
- ↑ Dubacq C, et al. (2002) Sgt1p contributes to cyclic AMP pathway activity and physically interacts with the adenylyl cyclase Cyr1p/Cdc35p in budding yeast. Eukaryot Cell 1(4):568-82 SGD PMID 12456005
- ↑ Kitagawa K, et al. (1999) SGT1 encodes an essential component of the yeast kinetochore assembly pathway and a novel subunit of the SCF ubiquitin ligase complex. Mol Cell 4(1):21-33 SGD PMID 10445024
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