Difference between revisions of "YJL034W"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000003571 YJL034W] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''KAR2 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''KAR2 '' | ||
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
| − | |nowrap| Chr X: | + | |nowrap| Chr X:381327..383375 |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000003571 | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000003571 | ||
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| − | '''Description of YJL034W:''' ATPase involved in protein import into the ER, also acts as a chaperone to mediate protein folding in the ER and may play a role in ER export of soluble proteins; regulates the unfolded protein response via interaction with Ire1p<ref name='S000059115'>Okamura K, et al. (2000) Dissociation of Kar2p/BiP from an ER sensory molecule, Ire1p, triggers the unfolded protein response in yeast. Biochem Biophys Res Commun 279(2):445-50 {{SGDpaper|S000059115}} PMID 11118306</ref><ref name=' | + | '''Description of YJL034W:''' ATPase involved in protein import into the ER, also acts as a chaperone to mediate protein folding in the ER and may play a role in ER export of soluble proteins; regulates the unfolded protein response via interaction with Ire1p<ref name='S000059115'>Okamura K, et al. (2000) Dissociation of Kar2p/BiP from an ER sensory molecule, Ire1p, triggers the unfolded protein response in yeast. Biochem Biophys Res Commun 279(2):445-50 {{SGDpaper|S000059115}} PMID 11118306</ref><ref name='S000044438'>Romisch K (1999) Surfing the Sec61 channel: bidirectional protein translocation across the ER membrane. J Cell Sci 112 ( Pt 23)():4185-91 {{SGDpaper|S000044438}} PMID 10564637</ref><ref name='S000055090'>Tokunaga M, et al. (1992) Purification and characterization of BiP/Kar2 protein from Saccharomyces cerevisiae. J Biol Chem 267(25):17553-9 |
| − | {{SGDpaper| | + | {{SGDpaper|S000055090}} PMID 1325440</ref> |
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Latest revision as of 07:45, 23 January 2012
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| Systematic name | YJL034W |
| Gene name | KAR2 |
| Aliases | GRP78 |
| Feature type | ORF, Verified |
| Coordinates | Chr X:381327..383375 |
| Primary SGDID | S000003571 |
Description of YJL034W: ATPase involved in protein import into the ER, also acts as a chaperone to mediate protein folding in the ER and may play a role in ER export of soluble proteins; regulates the unfolded protein response via interaction with Ire1p[1][2][3]
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References
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- ↑ Okamura K, et al. (2000) Dissociation of Kar2p/BiP from an ER sensory molecule, Ire1p, triggers the unfolded protein response in yeast. Biochem Biophys Res Commun 279(2):445-50 SGD PMID 11118306
- ↑ Romisch K (1999) Surfing the Sec61 channel: bidirectional protein translocation across the ER membrane. J Cell Sci 112 ( Pt 23)():4185-91 SGD PMID 10564637
- ↑ Tokunaga M, et al. (1992) Purification and characterization of BiP/Kar2 protein from Saccharomyces cerevisiae. J Biol Chem 267(25):17553-9 SGD PMID 1325440
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