Difference between revisions of "YDR277C"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000002685 YDR277C]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000002685 YDR277C]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''MTH1 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''MTH1 ''
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
|nowrap| Chr IV:1015699..1014398
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|nowrap| Chr IV:1015702..1014401
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000002685
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000002685
 
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'''Description of YDR277C:''' Negative regulator of the glucose-sensing signal transduction pathway, required for repression of transcription by Rgt1p; interacts with Rgt1p and the Snf3p and Rgt2p glucose sensors; phosphorylated by Yck1p, triggering Mth1p degradation<ref name='S000074769'>Moriya H and Johnston M (2004) Glucose sensing and signaling in Saccharomyces cerevisiae through the Rgt2 glucose sensor and casein kinase I. Proc Natl Acad Sci U S A 101(6):1572-7 {{SGDpaper|S000074769}} PMID 14755054</ref><ref name='S000074291'>Lakshmanan J, et al. (2003) Repression of transcription by Rgt1 in the absence of glucose requires Std1 and Mth1. Curr Genet 44(1):19-25 {{SGDpaper|S000074291}} PMID 14508605</ref><ref name='S000055223'>Lafuente MJ, et al. (2000) Mth1 receives the signal given by the glucose sensors Snf3 and Rgt2 in Saccharomyces cerevisiae. Mol Microbiol 35(1):161-72
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'''Description of YDR277C:''' Negative regulator of the glucose-sensing signal transduction pathway, required for repression of transcription by Rgt1p; interacts with Rgt1p and the Snf3p and Rgt2p glucose sensors; phosphorylated by Yck1p, triggering Mth1p degradation<ref name='S000055223'>Lafuente MJ, et al. (2000) Mth1 receives the signal given by the glucose sensors Snf3 and Rgt2 in Saccharomyces cerevisiae. Mol Microbiol 35(1):161-72 {{SGDpaper|S000055223}} PMID 10632886</ref><ref name='S000074291'>Lakshmanan J, et al. (2003) Repression of transcription by Rgt1 in the absence of glucose requires Std1 and Mth1. Curr Genet 44(1):19-25 {{SGDpaper|S000074291}} PMID 14508605</ref><ref name='S000074769'>Moriya H and Johnston M (2004) Glucose sensing and signaling in Saccharomyces cerevisiae through the Rgt2 glucose sensor and casein kinase I. Proc Natl Acad Sci U S A 101(6):1572-7
  {{SGDpaper|S000055223}} PMID 10632886</ref>
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  {{SGDpaper|S000074769}} PMID 14755054</ref>
 
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Latest revision as of 06:45, 23 January 2012

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Systematic name YDR277C
Gene name MTH1
Aliases BPC1, DGT1, HTR1
Feature type ORF, Verified
Coordinates Chr IV:1015702..1014401
Primary SGDID S000002685


Description of YDR277C: Negative regulator of the glucose-sensing signal transduction pathway, required for repression of transcription by Rgt1p; interacts with Rgt1p and the Snf3p and Rgt2p glucose sensors; phosphorylated by Yck1p, triggering Mth1p degradation[1][2][3]




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References

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  1. Lafuente MJ, et al. (2000) Mth1 receives the signal given by the glucose sensors Snf3 and Rgt2 in Saccharomyces cerevisiae. Mol Microbiol 35(1):161-72 SGD PMID 10632886
  2. Lakshmanan J, et al. (2003) Repression of transcription by Rgt1 in the absence of glucose requires Std1 and Mth1. Curr Genet 44(1):19-25 SGD PMID 14508605
  3. Moriya H and Johnston M (2004) Glucose sensing and signaling in Saccharomyces cerevisiae through the Rgt2 glucose sensor and casein kinase I. Proc Natl Acad Sci U S A 101(6):1572-7 SGD PMID 14755054

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