Difference between revisions of "YDR085C"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000002492 YDR085C] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''AFR1 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''AFR1 '' | ||
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
| − | |nowrap| Chr IV: | + | |nowrap| Chr IV:616150..614288 |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000002492 | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000002492 | ||
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| − | '''Description of YDR085C:''' | + | '''Description of YDR085C:''' Protein required for pheromone-induced projection (shmoo) formation; regulates septin architecture during mating; has an RVXF motif that mediates targeting of Glc7p to mating projections; interacts with Cdc12p; AFR1 has a paralog, YER158C, that arose from the whole genome duplication<ref name='S000126719'>Bharucha JP, et al. (2008) Saccharomyces cerevisiae Afr1 protein is a protein phosphatase 1/Glc7-targeting subunit that regulates the septin cytoskeleton during mating. Eukaryot Cell 7(8):1246-55 {{SGDpaper|S000126719}} PMID 18552279</ref><ref name='S000113653'>Byrne KP and Wolfe KH (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61 {{SGDpaper|S000113653}} PMID 16169922</ref><ref name='S000122697'>Changwei Z, et al. (2007) Afr1p has a role in regulating the localization of Mpk1p at the shmoo tip in Saccharomyces cerevisiae. FEBS Lett 581(14):2670-4 {{SGDpaper|S000122697}} PMID 17509572</ref><ref name='S000039269'>DeMattei CR, et al. (2000) Point mutations identify a conserved region of the saccharomyces cerevisiae AFR1 gene that is essential for both the pheromone signaling and morphogenesis functions. Genetics 155(1):43-55 {{SGDpaper|S000039269}} PMID 10790383</ref><ref name='S000051757'>Giot L and Konopka JB (1997) Functional analysis of the interaction between Afr1p and the Cdc12p septin, two proteins involved in pheromone-induced morphogenesis. Mol Biol Cell 8(6):987-98 {{SGDpaper|S000051757}} PMID 9201710</ref><ref name='S000041075'>Konopka JB (1993) AFR1 acts in conjunction with the alpha-factor receptor to promote morphogenesis and adaptation. Mol Cell Biol 13(11):6876-88 |
| − | + | {{SGDpaper|S000041075}} PMID 8413281</ref> | |
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Latest revision as of 13:05, 20 October 2012
Share your knowledge...Edit this entry! <protect>
| Systematic name | YDR085C |
| Gene name | AFR1 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr IV:616150..614288 |
| Primary SGDID | S000002492 |
Description of YDR085C: Protein required for pheromone-induced projection (shmoo) formation; regulates septin architecture during mating; has an RVXF motif that mediates targeting of Glc7p to mating projections; interacts with Cdc12p; AFR1 has a paralog, YER158C, that arose from the whole genome duplication[1][2][3][4][5][6]
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References
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- ↑ Bharucha JP, et al. (2008) Saccharomyces cerevisiae Afr1 protein is a protein phosphatase 1/Glc7-targeting subunit that regulates the septin cytoskeleton during mating. Eukaryot Cell 7(8):1246-55 SGD PMID 18552279
- ↑ Byrne KP and Wolfe KH (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61 SGD PMID 16169922
- ↑ Changwei Z, et al. (2007) Afr1p has a role in regulating the localization of Mpk1p at the shmoo tip in Saccharomyces cerevisiae. FEBS Lett 581(14):2670-4 SGD PMID 17509572
- ↑ DeMattei CR, et al. (2000) Point mutations identify a conserved region of the saccharomyces cerevisiae AFR1 gene that is essential for both the pheromone signaling and morphogenesis functions. Genetics 155(1):43-55 SGD PMID 10790383
- ↑ Giot L and Konopka JB (1997) Functional analysis of the interaction between Afr1p and the Cdc12p septin, two proteins involved in pheromone-induced morphogenesis. Mol Biol Cell 8(6):987-98 SGD PMID 9201710
- ↑ Konopka JB (1993) AFR1 acts in conjunction with the alpha-factor receptor to promote morphogenesis and adaptation. Mol Cell Biol 13(11):6876-88 SGD PMID 8413281
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