Difference between revisions of "YKR080W"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000001788 YKR080W] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''MTD1 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''MTD1 '' | ||
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
| − | |nowrap| Chr XI: | + | |nowrap| Chr XI:590395..591357 |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000001788 | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000001788 | ||
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| − | '''Description of YKR080W:''' NAD-dependent 5,10-methylenetetrahydrafolate dehydrogenase, plays a catalytic role in oxidation of cytoplasmic one-carbon units; expression is regulated by Bas1p and Bas2p, repressed by adenine, and may be induced by inositol and choline<ref name='S000074120'>Santiago TC and Mamoun CB (2003) Genome expression analysis in yeast reveals novel transcriptional regulation by inositol and choline and new regulatory functions for Opi1p, Ino2p, and Ino4p. J Biol Chem 278(40):38723-30 {{SGDpaper|S000074120}} PMID 12871953 | + | '''Description of YKR080W:''' NAD-dependent 5,10-methylenetetrahydrafolate dehydrogenase, plays a catalytic role in oxidation of cytoplasmic one-carbon units; expression is regulated by Bas1p and Bas2p, repressed by adenine, and may be induced by inositol and choline<ref name='S000053545'>Denis V and Daignan-Fornier B (1998) Synthesis of glutamine, glycine and 10-formyl tetrahydrofolate is coregulated with purine biosynthesis in Saccharomyces cerevisiae. Mol Gen Genet 259(3):246-55 {{SGDpaper|S000053545}} PMID 9749667</ref><ref name='S000074120'>Santiago TC and Mamoun CB (2003) Genome expression analysis in yeast reveals novel transcriptional regulation by inositol and choline and new regulatory functions for Opi1p, Ino2p, and Ino4p. J Biol Chem 278(40):38723-30 {{SGDpaper|S000074120}} PMID 12871953</ref><ref name='S000039764'>West MG, et al. (1996) Metabolic role of cytoplasmic isozymes of 5,10-methylenetetrahydrofolate dehydrogenase in Saccharomyces cerevisiae. Biochemistry 35(9):3122-32 |
{{SGDpaper|S000039764}} PMID 8608153</ref> | {{SGDpaper|S000039764}} PMID 8608153</ref> | ||
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Latest revision as of 06:45, 23 January 2012
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| Systematic name | YKR080W |
| Gene name | MTD1 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr XI:590395..591357 |
| Primary SGDID | S000001788 |
Description of YKR080W: NAD-dependent 5,10-methylenetetrahydrafolate dehydrogenase, plays a catalytic role in oxidation of cytoplasmic one-carbon units; expression is regulated by Bas1p and Bas2p, repressed by adenine, and may be induced by inositol and choline[1][2][3]
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References
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- ↑ Denis V and Daignan-Fornier B (1998) Synthesis of glutamine, glycine and 10-formyl tetrahydrofolate is coregulated with purine biosynthesis in Saccharomyces cerevisiae. Mol Gen Genet 259(3):246-55 SGD PMID 9749667
- ↑ Santiago TC and Mamoun CB (2003) Genome expression analysis in yeast reveals novel transcriptional regulation by inositol and choline and new regulatory functions for Opi1p, Ino2p, and Ino4p. J Biol Chem 278(40):38723-30 SGD PMID 12871953
- ↑ West MG, et al. (1996) Metabolic role of cytoplasmic isozymes of 5,10-methylenetetrahydrofolate dehydrogenase in Saccharomyces cerevisiae. Biochemistry 35(9):3122-32 SGD PMID 8608153
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