Difference between revisions of "YDR165W"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000002572 YDR165W]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000002572 YDR165W]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''TRM82 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''TRM82 ''
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
|nowrap| Chr IV:784869..786203
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|nowrap| Chr IV:784871..786205
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000002572
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000002572
 
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'''Description of YDR165W:''' Subunit of a tRNA methyltransferase complex composed of Trm8p and Trm82p that catalyzes 7-methylguanosine modification of tRNA<ref name='S000122114'>Matsumoto K, et al. (2007) RNA recognition mechanism of eukaryote tRNA (m(7)G46) methyltransferase (Trm8-Trm82 complex). FEBS Lett 581(8):1599-604 {{SGDpaper|S000122114}} PMID 17382321</ref><ref name='S000071564'>Alexandrov A, et al. (2002) Two proteins that form a complex are required for 7-methylguanosine modification of yeast tRNA. RNA 8(10):1253-66
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'''Description of YDR165W:''' Catalytic subunit of a tRNA methyltransferase complex; Trm8p and Trm82p comprise an enzyme that catalyzes a methyl-transfer from S-adenosyl-l-methionine to the N(7) atom of guanine at position 46 in tRNA; Trm8 lacks catalytic activity if not bound to Trm82p<ref name='S000071564'>Alexandrov A, et al. (2002) Two proteins that form a complex are required for 7-methylguanosine modification of yeast tRNA. RNA 8(10):1253-66 {{SGDpaper|S000071564}} PMID 12403464</ref><ref name='S000125212'>Leulliot N, et al. (2008) Structure of the Yeast tRNA m7G Methylation Complex. Structure 16(1):52-61 {{SGDpaper|S000125212}} PMID 18184583</ref><ref name='S000122114'>Matsumoto K, et al. (2007) RNA recognition mechanism of eukaryote tRNA (m(7)G46) methyltransferase (Trm8-Trm82 complex). FEBS Lett 581(8):1599-604 {{SGDpaper|S000122114}} PMID 17382321</ref><ref name='S000125097'>Matsumoto K, et al. (2008) Production of yeast tRNA (m(7)G46) methyltransferase (Trm8-Trm82 complex) in a wheat germ cell-free translation system. J Biotechnol 133(4):453-60
  {{SGDpaper|S000071564}} PMID 12403464</ref>
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  {{SGDpaper|S000125097}} PMID 18164779</ref>
 
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Latest revision as of 06:45, 23 January 2012

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Systematic name YDR165W
Gene name TRM82
Aliases
Feature type ORF, Verified
Coordinates Chr IV:784871..786205
Primary SGDID S000002572


Description of YDR165W: Catalytic subunit of a tRNA methyltransferase complex; Trm8p and Trm82p comprise an enzyme that catalyzes a methyl-transfer from S-adenosyl-l-methionine to the N(7) atom of guanine at position 46 in tRNA; Trm8 lacks catalytic activity if not bound to Trm82p[1][2][3][4]




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References

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  1. Alexandrov A, et al. (2002) Two proteins that form a complex are required for 7-methylguanosine modification of yeast tRNA. RNA 8(10):1253-66 SGD PMID 12403464
  2. Leulliot N, et al. (2008) Structure of the Yeast tRNA m7G Methylation Complex. Structure 16(1):52-61 SGD PMID 18184583
  3. Matsumoto K, et al. (2007) RNA recognition mechanism of eukaryote tRNA (m(7)G46) methyltransferase (Trm8-Trm82 complex). FEBS Lett 581(8):1599-604 SGD PMID 17382321
  4. Matsumoto K, et al. (2008) Production of yeast tRNA (m(7)G46) methyltransferase (Trm8-Trm82 complex) in a wheat germ cell-free translation system. J Biotechnol 133(4):453-60 SGD PMID 18164779

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