Difference between revisions of "YGL143C"
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− | '''Description of YGL143C:''' Mitochondrial | + | '''Description of YGL143C:''' Mitochondrial translation release factor, involved in stop codon recognition and hydrolysis of the peptidyl-tRNA bond during mitochondrial translation; lack of MRF1 causes mitochondrial genome instability<ref name='S000075917'>Towpik J, et al. (2004) Mutations in the yeast mrf1 gene encoding mitochondrial release factor inhibit translation on mitochondrial ribosomes. J Biol Chem 279(14):14096-103 {{SGDpaper|S000075917}} PMID 14734569</ref><ref name='S000040823'>Pel HJ, et al. (1992) The yeast nuclear gene MRF1 encodes a mitochondrial peptide chain release factor and cures several mitochondrial RNA splicing defects. Nucleic Acids Res 20(23):6339-46 |
{{SGDpaper|S000040823}} PMID 1475194</ref> | {{SGDpaper|S000040823}} PMID 1475194</ref> | ||
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Revision as of 14:05, 17 August 2007
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Systematic name | YGL143C |
Gene name | MRF1 |
Aliases | |
Feature type | ORF, Verified |
Coordinates | Chr VII:235963..234722 |
Primary SGDID | S000003111 |
Description of YGL143C: Mitochondrial translation release factor, involved in stop codon recognition and hydrolysis of the peptidyl-tRNA bond during mitochondrial translation; lack of MRF1 causes mitochondrial genome instability[1][2]
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Contents
Community Commentary
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DNA and RNA Details
Other DNA and RNA Details
Other Topic: expression
Specifically higher expression in carbon limited chemostat cultures versus carbon excess. [3] [4]
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References
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- ↑ Towpik J, et al. (2004) Mutations in the yeast mrf1 gene encoding mitochondrial release factor inhibit translation on mitochondrial ribosomes. J Biol Chem 279(14):14096-103 SGD PMID 14734569
- ↑ Pel HJ, et al. (1992) The yeast nuclear gene MRF1 encodes a mitochondrial peptide chain release factor and cures several mitochondrial RNA splicing defects. Nucleic Acids Res 20(23):6339-46 SGD PMID 1475194
- ↑ Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. J Biol Chem 278(5):3265-74 SGD PMID 12414795
- ↑ submitted by Viktor Boer on 2003-07-25
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