Difference between revisions of "YPR018W"
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| − | '''Description of YPR018W:''' Largest subunit (p90) of the Chromatin Assembly Complex (CAF- | + | '''Description of YPR018W:''' Largest subunit (p90) of the Chromatin Assembly Complex (CAF-1) with Cac2p and Msi1p that assembles newly synthesized histones onto recently replicated DNA; involved in the maintenance of transcriptionally silent chromatin<ref name='S000080189'>Glowczewski L, et al. (2004) Yeast chromatin assembly complex 1 protein excludes nonacetylatable forms of histone H4 from chromatin and the nucleus. Mol Cell Biol 24(23):10180-92 {{SGDpaper|S000080189}} PMID 15542829</ref><ref name='S000081084'>Adams CR and Kamakaka RT (1999) Chromatin assembly: biochemical identities and genetic redundancy. Curr Opin Genet Dev 9(2):185-90 |
{{SGDpaper|S000081084}} PMID 10322140</ref> | {{SGDpaper|S000081084}} PMID 10322140</ref> | ||
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Revision as of 13:05, 9 April 2007
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| Systematic name | YPR018W |
| Gene name | RLF2 |
| Aliases | CAC1 |
| Feature type | ORF, Verified |
| Coordinates | Chr XVI:594473..596293 |
| Primary SGDID | S000006222 |
Description of YPR018W: Largest subunit (p90) of the Chromatin Assembly Complex (CAF-1) with Cac2p and Msi1p that assembles newly synthesized histones onto recently replicated DNA; involved in the maintenance of transcriptionally silent chromatin[1][2]
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Protein Details
Protein Modification
Modification(s): Phosphorylation
Identified as an efficient substrate of Clb2-Cdk1-as1 in a screen of a proteomic GST-fusion library. [3] [4]
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References
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- ↑ Glowczewski L, et al. (2004) Yeast chromatin assembly complex 1 protein excludes nonacetylatable forms of histone H4 from chromatin and the nucleus. Mol Cell Biol 24(23):10180-92 SGD PMID 15542829
- ↑ Adams CR and Kamakaka RT (1999) Chromatin assembly: biochemical identities and genetic redundancy. Curr Opin Genet Dev 9(2):185-90 SGD PMID 10322140
- ↑ Ubersax JA, et al. (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64 SGD PMID 14574415
- ↑ submitted by Jeff Ubersax on 2004-01-29
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