|
|
| Line 1: |
Line 1: |
| − | <!-- PLEASE DO NOT EDIT HERE. USE THE SECTION EDIT LINKS ON THE RIGHT MARGIN-->
| + | #REDIRECT [[YBR008C]] |
| − | {{PageTop}}
| |
| − | <protect>
| |
| − | {|{{Prettytable}} align = 'right' width = '200px'
| |
| − | |-
| |
| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?locus=YBR008C YBR008C]
| |
| − | |-
| |
| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''FLR1 ''
| |
| − | |-
| |
| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Aliases''' ||'' ''
| |
| − | |-
| |
| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Feature type''' || ORF, Verified[[Category:ORF]][[Category:ORF, Verified]]
| |
| − | |-
| |
| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
| |
| − | |nowrap| Chr II:254210..252564
| |
| − | |}
| |
| − | <br>
| |
| − | '''Description of {{PAGENAME}}:''' Plasma membrane multidrug transporter, member of the major facilitator superfamily; involved in efflux of fluconazole, diazaborine, benomyl, methotrexate, and other drugs<ref name='S000052308'>Alarco AM, et al. (1997) AP1-mediated multidrug resistance in Saccharomyces cerevisiae requires FLR1 encoding a transporter of the major facilitator superfamily. J Biol Chem 272(31):19304-13 {{SGDpaper|S000052308}} PMID 9235926</ref><ref name='S000044268'>Jungwirth H, et al. (2000) Diazaborine resistance in yeast involves the efflux pumps Ycf1p and Flr1p and is enhanced by a gain-of-function allele of gene YAP1. Eur J Biochem 267(15):4809-16 {{SGDpaper|S000044268}} PMID 10903515</ref><ref name='S000042127'>Broco N, et al. (1999) FLR1 gene (ORF YBR008c) is required for benomyl and methotrexate resistance in Saccharomyces cerevisiae and its benomyl-induced expression is dependent on pdr3 transcriptional regulator. Yeast 15(15):1595-608
| |
| − | {{SGDpaper|S000042127}} PMID 10572257</ref>
| |
| − | <br>
| |
| − | <br>
| |
| − | <br>
| |
| − | <br>
| |
| − | <br>
| |
| − | </protect>
| |
| − | __TOC__
| |
| − | ==Community Commentary==
| |
| − | {{CommentaryHelp}}
| |
| − | | |
| − | | |
| − | | |
| − | <protect>
| |
| − | ==References==
| |
| − | <!-- REFERENCES ARE AUTOMATICALLY GENERATED. PLEASE DON'T EDIT THIS SECTION-->
| |
| − | {{RefHelp}}
| |
| − | </protect>
| |
