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| + | #REDIRECT [[YAR003W]] |
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− | {|{{Prettytable}} align = 'right' width = '200px'
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− | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?locus=YAR003W YAR003W]
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− | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''SWD1 ''
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− | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Aliases''' ||''CPS50, FUN16, SAF49''
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− | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Feature type''' || ORF, Verified[[Category:ORF]][[Category:ORF, Verified]]
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− | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
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− | |nowrap| Chr I:155007..156287
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− | |}
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− | '''Description of {{PAGENAME}}:''' Subunit of the COMPASS (Set1C) complex, which methylates histone H3 on lysine 4 and is required in transcriptional silencing near telomeres; WD40 beta propeller superfamily member with similarity to mammalian Rbbp7<ref name='S000076083'>Cheng H, et al. (2004) The essential WD repeat protein Swd2 has dual functions in RNA polymerase II transcription termination and lysine 4 methylation of histone H3. Mol Cell Biol 24(7):2932-43 {{SGDpaper|S000076083}} PMID 15024081</ref><ref name='S000070308'>Dover J, et al. (2002) Methylation of histone H3 by COMPASS requires ubiquitination of histone H2B by Rad6. J Biol Chem 277(32):28368-71 {{SGDpaper|S000070308}} PMID 12070136</ref><ref name='S000069538'>Krogan NJ, et al. (2002) COMPASS, a histone H3 (Lysine 4) methyltransferase required for telomeric silencing of gene expression. J Biol Chem 277(13):10753-5 {{SGDpaper|S000069538}} PMID 11805083</ref><ref name='S000068991'>Nagy PL, et al. (2002) A trithorax-group complex purified from Saccharomyces cerevisiae is required for methylation of histone H3. Proc Natl Acad Sci U S A 99(1):90-4 {{SGDpaper|S000068991}} PMID 11752412</ref><ref name='S000068755'>Roguev A, et al. (2001) The Saccharomyces cerevisiae Set1 complex includes an Ash2 homologue and methylates histone 3 lysine 4. EMBO J 20(24):7137-48 {{SGDpaper|S000068755}} PMID 11742990</ref><ref name='S000066156'>Miller T, et al. (2001) COMPASS: a complex of proteins associated with a trithorax-related SET domain protein. Proc Natl Acad Sci U S A 98(23):12902-7
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− | {{SGDpaper|S000066156}} PMID 11687631</ref>
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− | __TOC__
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− | ==Community Commentary==
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− | ==References==
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− | {{RefHelp}}
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