Difference between revisions of "YBL071W-A"

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{|{{Prettytable}} align = 'right' width = '200px'
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?locus=YBL071W-A YBL071W-A]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000007587 YBL071W-A]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''KTI11 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''KTI11 ''
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|nowrap| Chr II:89976..90224
 
|nowrap| Chr II:89976..90224
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000007587
 
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'''Description of {{PAGENAME}}:''' Protein required for synthesis of diphthamide, a modified histidine residue of translation elongation factor 2; functions with Dph1p, Dph2p, Jjj3p, and Dph5p; required, with Elongator complex, for modification of wobble nucleosides in tRNA<ref name='S000079857'>Liu S, et al. (2004) Identification of the proteins required for biosynthesis of diphthamide, the target of bacterial ADP-ribosylating toxins on translation elongation factor 2. Mol Cell Biol 24(21):9487-97 {{SGDpaper|S000079857}} PMID 15485916</ref><ref name='S000081138'>Huang B, et al. (2005) An early step in wobble uridine tRNA modification requires the Elongator complex. RNA 11(4):424-36 {{SGDpaper|S000081138}} PMID 15769872</ref><ref name='S000069896'>Fichtner L and Schaffrath R (2002) KTI11 and KTI13, Saccharomyces cerevisiae genes controlling sensitivity to G1 arrest induced by Kluyveromyces lactis zymocin. Mol Microbiol 44(3):865-75
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'''Description of YBL071W-A:''' Protein required for synthesis of diphthamide, a modified histidine residue of translation elongation factor 2; functions with Dph1p, Dph2p, Jjj3p, and Dph5p; required, with Elongator complex, for modification of wobble nucleosides in tRNA<ref name='S000079857'>Liu S, et al. (2004) Identification of the proteins required for biosynthesis of diphthamide, the target of bacterial ADP-ribosylating toxins on translation elongation factor 2. Mol Cell Biol 24(21):9487-97 {{SGDpaper|S000079857}} PMID 15485916</ref><ref name='S000081138'>Huang B, et al. (2005) An early step in wobble uridine tRNA modification requires the Elongator complex. RNA 11(4):424-36 {{SGDpaper|S000081138}} PMID 15769872</ref><ref name='S000069896'>Fichtner L and Schaffrath R (2002) KTI11 and KTI13, Saccharomyces cerevisiae genes controlling sensitivity to G1 arrest induced by Kluyveromyces lactis zymocin. Mol Microbiol 44(3):865-75
 
  {{SGDpaper|S000069896}} PMID 11994165</ref>
 
  {{SGDpaper|S000069896}} PMID 11994165</ref>
 
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J Biol Chem 278(5):3265-74</ref>
 
J Biol Chem 278(5):3265-74</ref>
 
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Revision as of 07:46, 27 February 2007

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Systematic name YBL071W-A
Gene name KTI11
Aliases DPH3
Feature type ORF, Verified
Coordinates Chr II:89976..90224
Primary SGDID S000007587


Description of YBL071W-A: Protein required for synthesis of diphthamide, a modified histidine residue of translation elongation factor 2; functions with Dph1p, Dph2p, Jjj3p, and Dph5p; required, with Elongator complex, for modification of wobble nucleosides in tRNA[1][2][3]




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References

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  1. Liu S, et al. (2004) Identification of the proteins required for biosynthesis of diphthamide, the target of bacterial ADP-ribosylating toxins on translation elongation factor 2. Mol Cell Biol 24(21):9487-97 SGD PMID 15485916
  2. Huang B, et al. (2005) An early step in wobble uridine tRNA modification requires the Elongator complex. RNA 11(4):424-36 SGD PMID 15769872
  3. Fichtner L and Schaffrath R (2002) KTI11 and KTI13, Saccharomyces cerevisiae genes controlling sensitivity to G1 arrest induced by Kluyveromyces lactis zymocin. Mol Microbiol 44(3):865-75 SGD PMID 11994165

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