Difference between revisions of "YPR006C"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl? | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000006210 YPR006C] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''ICL2 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''ICL2 '' | ||
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
|nowrap| Chr XVI:568993..567266 | |nowrap| Chr XVI:568993..567266 | ||
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| + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000006210 | ||
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| − | '''Description of | + | '''Description of YPR006C:''' 2-methylisocitrate lyase of the mitochondrial matrix, functions in the methylcitrate cycle to catalyze the conversion of 2-methylisocitrate to succinate and pyruvate; ICL2 transcription is repressed by glucose and induced by ethanol<ref name='S000059330'>Luttik MA, et al. (2000) The Saccharomyces cerevisiae ICL2 gene encodes a mitochondrial 2-methylisocitrate lyase involved in propionyl-coenzyme A metabolism. J Bacteriol 182(24):7007-13 {{SGDpaper|S000059330}} PMID 11092862</ref><ref name='S000040047'>Heinisch JJ, et al. (1996) Molecular genetics of ICL2, encoding a non-functional isocitrate lyase in Saccharomyces cerevisiae. Yeast 12(13):1285-95 |
{{SGDpaper|S000040047}} PMID 8923733</ref> | {{SGDpaper|S000040047}} PMID 8923733</ref> | ||
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J Biol Chem 278(5):3265-74</ref> | J Biol Chem 278(5):3265-74</ref> | ||
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Revision as of 07:46, 27 February 2007
Share your knowledge...Edit this entry! <protect>
| Systematic name | YPR006C |
| Gene name | ICL2 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr XVI:568993..567266 |
| Primary SGDID | S000006210 |
Description of YPR006C: 2-methylisocitrate lyase of the mitochondrial matrix, functions in the methylcitrate cycle to catalyze the conversion of 2-methylisocitrate to succinate and pyruvate; ICL2 transcription is repressed by glucose and induced by ethanol[1][2]
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Contents
Community Commentary
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DNA and RNA Details
Other DNA and RNA Details
Other Topic: expression
Specifically higher expression in carbon limited chemostat cultures versus carbon excess. [3] [4]
Protein Details
Other Protein Details
Other Topic: Regulated by the diauxic shift (glycerol)
Apart from the overall increase in mitochondrial protein mass this protein is induced after the diauxic shift. [5] [6]
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References
See Help:References on how to add references
- ↑ Luttik MA, et al. (2000) The Saccharomyces cerevisiae ICL2 gene encodes a mitochondrial 2-methylisocitrate lyase involved in propionyl-coenzyme A metabolism. J Bacteriol 182(24):7007-13 SGD PMID 11092862
- ↑ Heinisch JJ, et al. (1996) Molecular genetics of ICL2, encoding a non-functional isocitrate lyase in Saccharomyces cerevisiae. Yeast 12(13):1285-95 SGD PMID 8923733
- ↑ Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. J Biol Chem 278(5):3265-74 SGD PMID 12414795
- ↑ submitted by Viktor Boer on 2003-07-25
- ↑ Ohlmeier S, et al. (2004) The yeast mitochondrial proteome, a study of fermentative and respiratory growth. J Biol Chem 279(6):3956-79 SGD PMID 14597615
- ↑ submitted by Steffen Ohlmeier on 2004-04-08
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