Difference between revisions of "YOR259C"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?locus=YOR259C YOR259C]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000005785 YOR259C]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''RPT4 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''RPT4 ''
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|nowrap| Chr XV:813708..812395
 
|nowrap| Chr XV:813708..812395
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000005785
 
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'''Description of {{PAGENAME}}:''' One of six ATPases of the 19S regulatory particle of the 26S proteasome involved in the degradation of ubiquitinated substrates; required for spindle pole body duplication; localized mainly to the nucleus throughout the cell cycle<ref name='S000065027'>Rubin DM, et al. (1998) Active site mutants in the six regulatory particle ATPases reveal multiple roles for ATP in the proteasome. EMBO J 17(17):4909-19 {{SGDpaper|S000065027}} PMID 9724628</ref><ref name='S000047509'>Russell SJ, et al. (1999) Subcellular localization, stoichiometry, and protein levels of 26 S proteasome subunits in yeast. J Biol Chem 274(31):21943-52 {{SGDpaper|S000047509}} PMID 10419517</ref><ref name='S000044886'>McDonald HB and Byers B (1997) A proteasome cap subunit required for spindle pole body duplication in yeast. J Cell Biol 137(3):539-53 {{SGDpaper|S000044886}} PMID 9151663</ref><ref name='S000044396'>Glickman MH, et al. (1998) The regulatory particle of the Saccharomyces cerevisiae proteasome. Mol Cell Biol 18(6):3149-62
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'''Description of YOR259C:''' One of six ATPases of the 19S regulatory particle of the 26S proteasome involved in the degradation of ubiquitinated substrates; required for spindle pole body duplication; localized mainly to the nucleus throughout the cell cycle<ref name='S000065027'>Rubin DM, et al. (1998) Active site mutants in the six regulatory particle ATPases reveal multiple roles for ATP in the proteasome. EMBO J 17(17):4909-19 {{SGDpaper|S000065027}} PMID 9724628</ref><ref name='S000047509'>Russell SJ, et al. (1999) Subcellular localization, stoichiometry, and protein levels of 26 S proteasome subunits in yeast. J Biol Chem 274(31):21943-52 {{SGDpaper|S000047509}} PMID 10419517</ref><ref name='S000044886'>McDonald HB and Byers B (1997) A proteasome cap subunit required for spindle pole body duplication in yeast. J Cell Biol 137(3):539-53 {{SGDpaper|S000044886}} PMID 9151663</ref><ref name='S000044396'>Glickman MH, et al. (1998) The regulatory particle of the Saccharomyces cerevisiae proteasome. Mol Cell Biol 18(6):3149-62
 
  {{SGDpaper|S000044396}} PMID 9584156</ref>
 
  {{SGDpaper|S000044396}} PMID 9584156</ref>
 
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J Biol Chem 278(5):3265-74</ref>
 
J Biol Chem 278(5):3265-74</ref>
 
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Revision as of 08:46, 27 February 2007

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Systematic name YOR259C
Gene name RPT4
Aliases CRL13, PCS1, SUG2
Feature type ORF, Verified
Coordinates Chr XV:813708..812395
Primary SGDID S000005785


Description of YOR259C: One of six ATPases of the 19S regulatory particle of the 26S proteasome involved in the degradation of ubiquitinated substrates; required for spindle pole body duplication; localized mainly to the nucleus throughout the cell cycle[1][2][3][4]




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References

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  1. Jump up Rubin DM, et al. (1998) Active site mutants in the six regulatory particle ATPases reveal multiple roles for ATP in the proteasome. EMBO J 17(17):4909-19 SGD PMID 9724628
  2. Jump up Russell SJ, et al. (1999) Subcellular localization, stoichiometry, and protein levels of 26 S proteasome subunits in yeast. J Biol Chem 274(31):21943-52 SGD PMID 10419517
  3. Jump up McDonald HB and Byers B (1997) A proteasome cap subunit required for spindle pole body duplication in yeast. J Cell Biol 137(3):539-53 SGD PMID 9151663
  4. Jump up Glickman MH, et al. (1998) The regulatory particle of the Saccharomyces cerevisiae proteasome. Mol Cell Biol 18(6):3149-62 SGD PMID 9584156

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