Difference between revisions of "YOL133W"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl? | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000005493 YOL133W] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''HRT1 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''HRT1 '' | ||
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
|nowrap| Chr XV:70325..70690 | |nowrap| Chr XV:70325..70690 | ||
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| + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000005493 | ||
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<br> | <br> | ||
| − | '''Description of | + | '''Description of YOL133W:''' RING finger containing subunit of Skp1-Cullin-F-box ubiquitin protein ligases (SCF); required for Gic2p, Far1p, Sic1p and Cln2p degradation; may tether Cdc34p (a ubiquitin conjugating enzyme or E2) and Cdc53p (a cullin) subunits of SCF<ref name='S000058476'>Zachariae W and Nasmyth K (1999) Whose end is destruction: cell division and the anaphase-promoting complex. Genes Dev 13(16):2039-58 {{SGDpaper|S000058476}} PMID 10465783</ref><ref name='S000056381'>Seol JH, et al. (1999) Cdc53/cullin and the essential Hrt1 RING-H2 subunit of SCF define a ubiquitin ligase module that activates the E2 enzyme Cdc34. Genes Dev 13(12):1614-26 {{SGDpaper|S000056381}} PMID 10385629</ref><ref name='S000044681'>Ohta T, et al. (1999) ROC1, a homolog of APC11, represents a family of cullin partners with an associated ubiquitin ligase activity. Mol Cell 3(4):535-41 {{SGDpaper|S000044681}} PMID 10230407</ref><ref name='S000044434'>Skowyra D, et al. (1999) Reconstitution of G1 cyclin ubiquitination with complexes containing SCFGrr1 and Rbx1. Science 284(5414):662-5 {{SGDpaper|S000044434}} PMID 10213692</ref><ref name='S000044433'>Kamura T, et al. (1999) Rbx1, a component of the VHL tumor suppressor complex and SCF ubiquitin ligase. Science 284(5414):657-61 {{SGDpaper|S000044433}} PMID 10213691</ref><ref name='S000042446'>Blondel M, et al. (2000) Isolation and characterization of HRT1 using a genetic screen for mutants unable to degrade Gic2p in saccharomyces cerevisiae. Genetics 155(3):1033-44 |
{{SGDpaper|S000042446}} PMID 10880467</ref> | {{SGDpaper|S000042446}} PMID 10880467</ref> | ||
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J Biol Chem 278(5):3265-74</ref> | J Biol Chem 278(5):3265-74</ref> | ||
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<protect> | <protect> | ||
Revision as of 08:46, 27 February 2007
Share your knowledge...Edit this entry! <protect>
| Systematic name | YOL133W |
| Gene name | HRT1 |
| Aliases | HRT2, RBX1, ROC1 |
| Feature type | ORF, Verified |
| Coordinates | Chr XV:70325..70690 |
| Primary SGDID | S000005493 |
Description of YOL133W: RING finger containing subunit of Skp1-Cullin-F-box ubiquitin protein ligases (SCF); required for Gic2p, Far1p, Sic1p and Cln2p degradation; may tether Cdc34p (a ubiquitin conjugating enzyme or E2) and Cdc53p (a cullin) subunits of SCF[1][2][3][4][5][6]
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Contents
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References
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- Jump up ↑ Zachariae W and Nasmyth K (1999) Whose end is destruction: cell division and the anaphase-promoting complex. Genes Dev 13(16):2039-58 SGD PMID 10465783
- Jump up ↑ Seol JH, et al. (1999) Cdc53/cullin and the essential Hrt1 RING-H2 subunit of SCF define a ubiquitin ligase module that activates the E2 enzyme Cdc34. Genes Dev 13(12):1614-26 SGD PMID 10385629
- Jump up ↑ Ohta T, et al. (1999) ROC1, a homolog of APC11, represents a family of cullin partners with an associated ubiquitin ligase activity. Mol Cell 3(4):535-41 SGD PMID 10230407
- Jump up ↑ Skowyra D, et al. (1999) Reconstitution of G1 cyclin ubiquitination with complexes containing SCFGrr1 and Rbx1. Science 284(5414):662-5 SGD PMID 10213692
- Jump up ↑ Kamura T, et al. (1999) Rbx1, a component of the VHL tumor suppressor complex and SCF ubiquitin ligase. Science 284(5414):657-61 SGD PMID 10213691
- Jump up ↑ Blondel M, et al. (2000) Isolation and characterization of HRT1 using a genetic screen for mutants unable to degrade Gic2p in saccharomyces cerevisiae. Genetics 155(3):1033-44 SGD PMID 10880467
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